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Search Results - Folic acid

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250 °C (523 K), decomp.

A key observation by researcher Lucy Wills in 1931 led to the identification of folate as the nutrient needed to prevent anemia during pregnancy. Dr. Wills demonstrated that anemia could be reversed with brewer's yeast. Folate was identified as the corrective substance in brewer's yeast in the late 1930s and was extracted from spinach leaves in 1941. It was first synthesized in 1946 by Yellapragada Subbarao.

Folate is necessary for the production and maintenance of new cells.[1] This is especially important during periods of rapid cell division and growth such as infancy and pregnancy. Folate is needed to synthesize DNA bases (most notably thymine, but also purine bases) needed for DNA replication. Thus folate deficiency hinders DNA synthesis and cell division, affecting most notably bone marrow and cancer, both of which participate in rapid cell division. RNA transcription, and subsequent protein synthesis, are less affected by folate deficiency as the mRNA can be recycled and used again (as opposed to DNA synthesis where a new genomic copy must be created). Since folate deficiency limits cell division, erythropoiesis, production of red blood cells (RBCs) is hindered and leads to megaloblastic anemia which is characterized by large immature RBCs. This pathology results from persistently thwarted attempts at normal DNA replication, DNA repair, and cell division and produces abnormally large cells (megaloblasts) with abundant cytoplasm capable of RNA and protein synthesis but with clumping and fragmentation of nuclear chromatin. Some of these large cells, although immature, are released early from the marrow in an attempt to compensate for the anemia caused by lack of RBCs. [2] Both adults and children need folate to make normal RBCs and prevent anemia.[3] Deficiency of folate in pregnant women has been implicated in neural tube defects and so many cereals sold in developed countries are enriched with folate to avoid such complications.

In the form of a series of tetrahydrofolate (THF) compounds, folate derivatives are substrates in a number of single-carbon-transfer reactions, and also are involved in the synthesis of dTMP (2'-deoxythymidine-5'-phosphate) from dUMP (2'-deoxyuridine-5'-phosphate). It is a substrate for an important reaction that involves vitamin B12 and it is necessary for the synthesis of DNA, required for all dividing cells.

Showing 1 to 25 of 100 Articles matching 'Folic acid' in related articles.
Pages: 1 | 2 | 3 | 4 | Next >>

1. Researchers study amino acid linked to artery disease
August 22, 2008

High levels of the amino acid homocysteine are often a risk factor for coronary artery disease. Researchers in Norway recently studied the effect of lowering those levels. Researchers thought they could “lower the risk for having further heart attacks and related disease,” said Dr. Marta Ebbing, a researcher at the Haukeland University Hospital in Norway. The study focused on more than 3,000 patients with coronary artery disease. Some received a daily dose of vitamin B-12, B-6 or folic acid. Others received a placebo or sugar pill. Patients’ homocysteine levels were monitore... (read more)

Author: patty patty

2. What You Must Know About Early Pregnancy Stages
August 15, 2008

Pregnancy, whether it was planned or not, is important for any woman. Also, it is important to take good care of your body while it is forming another life inside. If you suspect that you might be pregnant, there are things you should do as soon as possible to help your body be as healthy as it can be. It is important that you get enough of “the right substance” to help prevent birth defects. Your midwife or doctor might want you to be taking prenatal vitamins, and often extra folic acid, at this early pregnancy stage. It is also important to stop doing something that could get bad materi... (read more)

Author: Franklin Simanjuntak

3. 7 Best Foods for Diet
August 15, 2008

Fruits and vegetables are best foods for diet when it comes to weight loss; they keep you full on relatively few calories. Of course there are many super foods, some you've never heard of and others you've simply forgotten about. Here, I've listed few best foods so you can make a place for them on your table and improve your health without a doctor's prescription. * Avocados are a good source of heart-healthy monounsaturated fat, folic acid and potassium, which helps regulate blood pressure and relax muscles. It's a high fiber food and you'll also get protein, a good dose of vitamins A, E... (read more)

Author: Leong Tony

4. Twelve nutrients for a pregnant woman
July 07, 2008

Twelve Down to Earth important nutrients for a pregnant woman’s diet. The following prenatal food supplements are highly recommended to ensure both her own and her baby’s health. 1. Folic acid. There are possible associations between folic acid and cardiovascular defects and limb-reduction defects. Reasons why The U.S. Department of Health and Human Services recommends that all women of childbearing age eat at least 400 mcg per day to reduce the occurrence of serious brain and spinal cord birth defects. 2. Vitamin A. Good for both the growing baby and the mother. Helps in the ... (read more)

Author: David Molina

5. Crunchy Okra Family Food
July 03, 2008

Okra is a good source of both soluble and insoluble fiber, as well as vitamin B6 and folic acid. Admittedly, frying it is not for the health-conscious, but at least the good stuff is still there. So, okra is grown mainly in very warm climates and was probably brought to America from Africa three hundred years ago. It looks like a small, ridged pepper, but has a soft, almost fuzzy exterior rather than smooth like a pepper. The flavor is very mild. The thing about okra that usually turns people off is that when you slice it, the insides release this slippery, slimey substance. This actua... (read more)

Author: jaffar aashik

6. Prenatal VItamins...Are They Necessary
June 29, 2008

Prenatal vitamins have become very popular among some women because it is believed that they help prevent birth defects. It is probably a good idea to supplement with prenatal vitamins because during pregnancy, both the mother and the child have increased needs for certain nutrients like folic acid and iron during this time and prenatal vitamins will prove helpful. Women who are pregnant often find that their doctors prescribe a prenatal vitamin. However, evidence has emerged that even for those women that are planning to conceive can benefit from prenatal vitamins. Prenatal vitamins could pre... (read more)

Author: keith henry

7. Mediterranean Diet: How to Lower Cholesterol & Reduce Your Risk of Heart Disease by 22% with Dry Be
June 26, 2008

For centuries, legumes or dry beans, as they are commonly known, have been a staple food in the Mediterranean countries where they have played an important part in the fight against heart disease. Why? Because… - Legumes contain essential minerals and vitamins such as iron, magnesium, manganese, phosphorous, zinc, potassium, folic acid, and some of the B-complex vitamins. - They are low in fat and sodium which make them an ideal food to keep high cholesterol and high blood pressure at bay. - Legumes are also high in soluble fiber, the kind that lowers cholesterol. - They can hel... (read more)

Author: Emilia Klapp

8. What Do You Know About the B Vitamins?
June 13, 2008

Introduction Despite supplement advertisements that claim otherwise, vitamins do not provide the body with fuel for energy. Only carbohydrate, fat and protein are used for fuel. But because B vitamins help the body use that fuel, it is true that without B vitamins the body would lack energy. The B vitamins have common dietetic sources such as whole grains, legumes, eggs, dairy products, meat, meat organs, fish and yeast. They are soluble in water and are quickly assimilated by our body. Since they are also eliminated through the urine, we have to ingest them in a daily basis through our ... (read more)

Author: Emilia Klapp

9. Healthy Body-Healthy Sperm
June 03, 2008

There are a lot of myths surrounding sperm count and sperm health. The truth is that your sperm count can vary from day to day and can be affected by many things. If you are interested in increasing your sperm health or sperm count, there are a few things that you can do to help improve your chances of having healthy sperm. Take your vitamins. A daily multivitamin can help your body to become a good environment for sperm production. Zinc and Folic Acid have been shown to help in sperm production and increase sperm count for a lot of men. Keeping your body healthy can have a direct connection ... (read more)

Author: Infertility Specialist

10. Prevent Cancer by Eating Berries
June 02, 2008

It has been well established that a diet high in fruits and vegetables is helpful in preventing many diseases including cancer. What has also been feverishly investigated is the effects of berries on the body. Some researchers have studied the health benefit of specific berries while others have focused on isolating the health-promoting bioactive compounds that give berries their claim to fame. Some of the known cancer-preventive agents present in berries include vitamins A, C, and E and folic acid; calcium and selenium; beta-carotene, alpha-carotene, and lutein; phytosterols such as... (read more)

Author: Yuri Elkaim

11. Autoimmune Hemolytic Anemia - Causes, Symptoms and Treatment
May 05, 2008

Idiopathic autoimmune hemolytic anemia is a drop in the number of red blood cells due to a problem with the body's defense (immune) system. Folic acid deficiency anemia. Folic acid is a member of the vitamin B family. It is used in the production of new red blood cells. Some people do not get enough folic acid in their normal diet, so their bodies are unable to produce enough red blood cells. In other cases, the body may not be able to properly use the folic acid eaten. Causes Idiopathic autoimmune hemolytic anemia is an acquired disease that occurs when antibodies form against a p... (read more)

Author: Peter Hutch

12. Vitamins: A Guide to the B Complex Vitamins
April 25, 2008

There is a lot of discussion about the B complex vitamin and how it is essential for the body to perform a multitude of functions. However, the B complex vitamin is not simply one very complicated vitamin, as the name might suggest. There are actually eight B vitamins that are in the B complex vitamin as well as a few other related substances. The eight vitamins that make up the B complex vitamin are thiamine or vitamin B1, riboflavin or vitamin B2, niacin or vitamin B3, pyridoxine or vitamin B6, cobalamine or vitamin B12, folic acid, pantothenic acid and biotin. The other related substances ... (read more)

Author: Nicholas Tan

13. Vitamins: A Guide to the B6 Vitamin
April 25, 2008

The B6 vitamin, also known as pyridoxine, is one of the most versatile of the B vitamins and yet the body only requires a relatively small amount. The B6 vitamin works closely with all the other B vitamins, especially niacin, folic acid, and Cobalamin and contributes to numerous functions in the body. Amino acids are converted by the B6 vitamin into proteins and it is also required for transforming stored sugar within the body into essential energy. Basically, the B6 vitamin is essential for converting the proteins that are consumed into proteins that the body needs and also for converting th... (read more)

Author: Nicholas Tan

14. Get Nutrition for Dry, Brittle Nails
April 25, 2008

Brittle nails are usually not associated with a medical disease. Brittle fingernails are a common condition, occurring in about 20 % of people; more women than men develop brittle nails. 1 Brittle nails usually break or peel off in horizontal layers, starting at the nail's free end. Brittleness in the nail may be caused by trauma, such as repeated wetting and drying, repeated exposure to detergents and water, and excessive exposure to harsh solvents, such as those found in nail polish remover. A deficiency of folic acid and vitamin C can result in hangnails. Inadequate dietary essential ... (read more)

Author: Peter Hutch

15. Hypertension Natural Treatment- High Blood Pressure Herbal Treatments
April 20, 2008

Here's the best advice you'll hear today, "Throw away your high blood pressure medications and begin a hypertension natural treatment that has been proven just as effective has diuretics." In fact, you can actually avoid all side effects and lower your high blood pressure points by 20% in less than 2 weeks. And if you are a skeptic, you should realize that your idea about medicine was molded by western medicine. But the truth about most healing treatments is that you don't need synthetic medicines to be cured of an ailment. If that was so, the human race would have never made it to t... (read more)

Author: Joe Barton

16. Essential Vitamins and Minerals to Save Your Hair
April 21, 2008

There are certain vitamins and minerals that you can take to prevent hair loss. However, the flip side is that excessive in take of vitamins can lead to hair loss. Some of the vital vitamins for preventing hair loss are B Vitamins as these are rich sources of Biotin, Magnesium, Folic Acid, Inositol, Sulfur and Zinc. According to a research, intake of these vitamins in prescribed amounts will reduce thinning of hair. According to experts, a diet low in magnesium causes hair loss in patches. Similarly, diet low in biotin or Inositol results in total baldness. When you take essenti... (read more)

Author: Bertil Hjert

17. Vitamin B complex: Benefits, Side Effects and Deficiency
April 16, 2008

We all need vitamins and minerals to keep us healthy and strong. These are essential to our overall well being and the state of our mind and body. How Can This Vitamin Help Me? Vitamin B complex, is a combination of several water soluble vitamins. The B complex group is made up of of eight B vitamins namely, B1(thiamine), B2(riboflovin), B3(niacin), B6(pyridoxine), B12(cobalamine), folic acid, panthothenic acid and biotin. Each of these vitamins has a distinctive function to perform in the body. Vitamin B complex helps in the healthy functioning of the immune and nervous system. It h... (read more)

Author: Dub Jackson

18. Weight Loss - Snacks That Keep Weight Off
April 15, 2008

Nuts alone or combined with a small box of raisins, makes a great high quality fiber-protein snack mix, to help keep your weight off. Nuts are high in protein, fiber and essential nutrients such as folic acid, potassium, magnesium, selenium and healthy monounsaturated fatty acids. Nuts, Particularly walnuts and almonds, have been shown in numerous studies to help prevent heart disease. A one-ounce serving of nuts either alone or combined with a small box of raisins, is an excellent way to boost your energy level and satisfy your appetite for many hours. Popcorn is a great high fiber, low ... (read more)

Author: Francis Adam

19. Prenatal Vitamins Are By No Means A Substitute For Healthy Eating
April 11, 2008

For pregnant women and all those who'd like to get pregnant, prenatal vitamins are highly important to support the formation of a new life. Vitamins and mineral supplements are necessary both before and during the pregnancy as such: thus, the folic acid intake should be twice larger than usual in the first trimester. Moreover, women who are planning to get pregnant should also administrate it in combination with calcium, iron and special prenatal vitamins recommended by the doctor. Though it is generally assumed that a woman will take all the vital elements from food, supplementation is often ... (read more)

Author: Muna wa Wanjiru

20. Health Benefits of Vitamin B Complex
April 02, 2008

There are eight B vitamins in vitamin B complex as well as several related substances. The eight vitamins are thiamine (B1), riboflavin (B2), niacin (B3), pyridoxine (B6), cobalamine (B12), folic acid, pantothenic acid and biotin. The other related substances include choline, inositol and para-aminobenzoic acid (PABA). Although each individual vitamin or related substance performs a different function in the body, they all work together to maintain good health and vitality. A well balanced diet should provide us with all the B vitamins we require, but because they are water soluble and... (read more)

Author: Corwin Brown

21. Bee Pollen Benefits
March 28, 2008

Bee pollen is one of nature’s healthiest and almost strong “superfoods. ” Bee Pollen contains digestive enzymes from the bees. It’s been used as a dietary supplementation for thousands of years. Bee pollen is frequently called nature’s ideal nutrient. Bee pollen combines 22 amino acids, vitamin C, B-complex and folic acid, polyunsaturated oily acids, enzymes, and carotene - all of the leading antioxidants that have then far been discovered. It is produced by flowering plants, which clings to bees as they assemble nectar. Bee pollen benefits are wonderful and chances are that you could better y... (read more)

Author: Juliet Cohen

22. Health Benefits of Wheat Grass
March 25, 2008

Wheatgrass is grown through a process known as sprouting. Sprouts are "complete foods" because they contain all other essential dietary nutrients, along with the enzymes to help assimilate them. They are easily digested and enter the bloodstream quickly. The nutrients in wheatgrass juice are completely assimilated by the human body in 20 minutes. For this reason sprouts are "quick energy" foods. Wheat sprouts contain four times more folic acid, and six times more Vitamin C, than unsprouted wheat or ordinary grass. Wheat grass is known as a powerful healing agent. Beyond the detoxification... (read more)

Author: Corwin Brown

23. Healthy Tips to Help With Conception
February 25, 2008

You and your partner have decided it’s time. You’ve stopped using birth control and you’ve begun the fun part of having kids, making them. Don’t stress out if you’re not pregnant in the first couple of months of trying. Here are some important things to keep in mind when trying to conceive. The body works best when it is not stressed out. Studies show that 8 out of 10 women suffer from significant stress in their day to day lives. Whether it is work, family, or financial stress it can wreak havoc on your system. Here are some simple ways you can work on reducing your stress level. If you... (read more)

Author: Eric Daiter

24. Get week by week guidance through your pregnancy.
February 22, 2008

Excitement, trepidation and maybe even slight fear are all understandable emotions once you find out you’re pregnant. But, many of the negative emotions can be cast aside by getting the best professional advice and following a step-by-step guide through your pregnancy. Indeed, getting solid advice from health professionals is the best way to ensure that your pregnancy progresses smoothly. Pregnancy is traditionally divided into three stages, or trimesters. The first trimester lasts until the 13th week of pregnancy, the second from 14 – 26 weeks and the final and third trimester from 27 we... (read more)

Author: Victoria Cochrane

25. Are You Taking Enough Vitamins During Pregnancy?
February 19, 2008

Whether you need supplements of vitamins during pregnancy is a debatable issue. However, most women are of the opinion that, prenatal vitamins are vital for fulfilling the requirement of nutrition during pregnancy. This holds particularly true when you have a deficiency. Common supplements of vitamins are those containing iron, folic acid, and other such crucial nutrients that you need during this nine-month phase. In case you are lactose-intolerant, the doctor may recommend you calcium supplements, to fulfill the increased calcium requirement in your body. Not all women are so ... (read more)

Author: apurva shree

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