Friderik “Fritz” Pregl (3 September
1869 – 13 December
1930) was an
Austrian-
Slovene physician and
chemist. He won the
Nobel Prize in Chemistry in 1923 for making important contributions to
quantitative organic microanalysis, one of which was the improvement of the
combustion train technique for
elemental analysis.
Pregl was born in Ljubljana within Austria-Hungary to a Slovene-speaking father and German-speaking mother. He died in Graz, Austria in 1930.
Pregl started his career as physician after he studied medicine at the University of Graz. With his focus on physiology and especially chemical physiology, he suffered from the limitations of quantitative organic microanalysis. The small quantities of substances he obtained during the research of Bile acid made it necessary improve the process of elemental analysis by reducing the necessary components. At the end of his research, he had lowered the minimal amount of substance necessary for the analysis process by a factor of 50. He invited chemists to learn his method of elemental analysis, so that the method was soon widely accepted.
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