Search Results - Genetic sequence
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A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology. The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA." Sequences can be derived from the biological raw material through a process called DNA sequencing. In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows[1]
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Showing 1 to 5 of 5 Articles matching 'Genetic sequence' in related articles. |
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1. Complete Genetic Sequence of Cow Revealed;
April 24, 2009
An international consortium of researchers has completed mapping the genetic blueprint of the domestic cow, a source of nutrition and livelihood for billions of people around the world. Scientists say the landmark accomplishment will lead to better food production and improvements in human medicine. The completed bovine genome map is the first full sequencing of a mammalian livestock species. It provides new insight into what makes a cow a cow and identifies important genetic traits that distinguish it from humans and other mammals. The map, published Friday in the journal Science, is the fru... (read more)
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2. Information about Genetic Diseases
June 11, 2008
Single-gene (also called Mendelian or monogenic) - This type is caused by changes or mutations that occur in the DNA sequence of one gene. Genes code for proteins, the molecules that carry out most of the work, perform most life functions, and even make up the majority of cellular structures. When a gene is mutated so that its protein product can no longer carry out its normal function, a disorder can result. There are more than 6,000 known single-gene disorders, which occur in about 1 out of every 200 births. Some examples are cystic fibrosis, sickle cell anemia, Marfan syndrome, Huntington’s... (read more)
Author: james Sameul
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3. RNA interference: Imgenex launched the pSuppressorAdeno construction kit for adenovirus mediated gen
December 03, 2007
RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals. The RNAi pathway is thought to be an ancient mechanism for protecting the host and its genome against viruses and rogue genetic elements that use double-stranded RNA (dsRNA) in their life cycles. They have also been shown to play a role not only in mRNA and dsRNA stability/degradation, but also in regulation of translation, transcription, chromatin structure, and genome integrity. In plants and animals,... (read more)
Author: Stephen Jones
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4. Scientists' Use of Woolly Mammoth DNA May Unlock Evolution of Elephant
September 27, 2007
An international team of scientists has unlocked the genetic blueprint of hair samples from ancient woolly mammoths found in Siberia. VOA's Jessica Berman reports the researchers say the DNA will give them valuable information about the evolution of elephants and possibly other prehistoric animals.
Scientists mapped the entire DNA sequence from the hair shafts of 13 Siberian woolly mammoths.
The mammoths roamed the earth 30,000 to 60,000 years ago and are the common, prehistoric ancestor of the African and Indian elephants.
The hair in the study was obtained from a frozen mammoth found in ... (read more)
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5. Scientists Unveil Genetic Blueprint Pinpointing Disease Genes
October 28, 2005
An international group of scientists has unveiled what's being called a "milestone for medical research." It's a genetic road map that should speed the discovery of genes that cause disease and assist in the development of new treatments. The so-called HapMap project is the outgrowth of the Human Genome Project unveiled in April 2003.
The fruit of the Human Genome Project was a rough draft unlocking the alphabet code of the 20,000 genes in our DNA.
These genetic building blocks, or genetic sequence, as it's known, are attached to two thread-like chromosomes wound tightly inside each cell. Th... (read more)
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