Biologics and Biosimilars World Markets

Table of contents : 1. Overview 18 1.1 Statement of This Report 18 1.2 About This Report 18 1.3 Scope of the Report 19 1.4 Objectives 20 1.5 Methodology 20 1.6 Executive Summary 21 2. Pharmaceutical Industry: An Overview 23 2.1 Global R&D Spending by Pharma and Biotech Companies 23 2.1.1 Top 20 Companies in R&D Spending 24 2.1.2 Top 20 Most Valuable Pharmaceutical R&D projects 24 2.1.3 Most Valuable R&D Projects Ranked by Net Present Value 25 2.2 FDA New Drug Approvals 26 2.2.1 Top Ten NMEs 27 2.3 Impact of Patent Expirations 27 2.4 Immunity of Pharmaceutical Growth against Drop in GDP Growth 28 2.5 Minimal Annual Growth Rates of Pharmaceuticals in Developed Markets 29 2.6 Falling Operating Profit Rate for Big Pharma 30 2.7 Top Ten Global Pharmaceutical Firms 30 2.6 Top Ten Pharmaceuticals by Sales Revenue 32 2.7 Worldwide Prescription and OTC Sales by Therapy Area in 2018 33 2.8 Top Companies in Oncology Sales 34 2.8.1 Top Five Oncology Products 35 2.9 Top Companies in Anti-Diabetes Market 36 2.9.1 Top Five Anti-Diabetes Products 36 2.10 Top Ten Companies in Anti-Rheumatics Market 37 2.10.1 Top Ten Anti-Rheumatics Products 37 2.11 Top Ten Vaccine Companies and Global Sales 38 2.11.1 Top Five Vaccine Products 38 2.12 Top Ten Anti-Viral Companies 39 2.12.1 Top Five Anti-Viral Products 39 2.13 Top 50 Global Pharmaceutical Brands in 2018 40 2.14 M&A Transactions in 2012 41 2.15 Global Pharmaceutical Market 42 2.15.1 Global Pharmaceutical Sales by Region 42 2.15.2 North American Pharmaceutical Market 43 2.15.2.1 U.S. Prescription Drug Sales by Company 44 2.15.2.2 Top 50 Pharmaceutical Products in the U.S. 45 2.15.2.3 Top 50 Products in the U.S. in 2018 47 2.15.3 Pharmaceutical Market in Europe 48 2.15.3.1 European Prescription Drug Sales by Company 49 2.15.4 Pharmaceutical Market in Asia/Pacific 50 2.15.4.1 Prescription Drug Sales in Japan by Company 51 2.15.5 Pharmaceutical Market in Latin America 52 2.15.6 Pharmaceutical Market in Africa 53 2.15.7 Pharmaceutical Market in the Middle East 54 2.16 Regional Prescription Drug Sales in the U.S., Europe and Japan 55 2.17 Global Prescription Drug Sales 55 3. Brand Name Pharmaceuticals: A Brief Overview 57 3.1 Birth Pangs and Life Span of Branded Drugs 57 3.2 Major Patent Expiries of Branded Drugs 58 3.3 Global Market for Branded Drugs 59 3.4 Increasing R & D Pipeline 59 3.4.1 The 2012 R & D Pipeline by Phase 60 3.4.2 Top Companies by Pipeline Size 61 3.4.3 Total Number of Companies with Active R&D 62 3.4.4 Global Distribution of Companies Active in Pharma R&D 63 3.4.5 Top Therapy Areas in R & D 64 3.4.5.1 Top 25 Individual Diseases in the R & D Pipeline 65 3.4.6 Top 20 Mechanism of Action in R & D Pipeline 66 3.4.7 Top 25 Drug Protein Targets 67 4. Generic Drugs: A Brief Overview 69 4.1 Bioequivalence of Generics 69 4.2 Global Market for Generics 70 4.3 Operating Profit Rate for Generic Companies 71 4.4 Outsourced Manufacture of Generics 72 4.5 Generic Utilization in International Markets 73 4.6 Global Generic Sales by Company 74 5. Biologics 76 5.1 Regulations for Biologics 76 5.2 Complexity of Biologics 76 5.3 Concentration of Global Biopharmaceutical Manufacturing 77 5.4 Number of Biologics Available in the Global Market 78 5.5 Share of Biologics by Country/Region 79 5.6 Rate of Growth for Biologics by Region 80 5.6.1 Growth Rates of APIs and Biologics Compared 80 5.7 Manufacturing Capacity of Biologics 81 5.8 Biologics Market by Segment 82 5.9 Patent Expiry for Biologic Drugs 83 5.9.1 India’s Opportunity from Biologic Patent Expirations 84 5.10 Major Players in Biologics 85 5.11 Biopharm Outsourcing 86 5.12 Top 20 Biologics by Sales 87 5.12.1 Roche’s Biologics Arsenal 88 5.12.2 Johnson & Johnson’s Biologics Arsenal 89 5.12.3 Lonza in Biologics 89 5.13 The Best Selling Biologics by Class 89 5.14 Biologic Drugs: Market Trends in the Past Seven Years 90 5.14.1 Global Market for Biologics 90 5.15 Global and U.S. Sales of Blockbuster Biologics 92 5.15.1 Global Market for Humira 92 5.15.1.1 Humira (adalimumab) Pen’s Market by Geography 92 5.15.1.2 U.S. Sales of Humira 93 5.15.1.3 The Leader among Biologics 94 5.15.2 Global Market for Remicade 94 5.15.2.1 Remicade’s Market by Geography 95 5.15.2.2 U.S. Sales of Remicade 96 5.15.3 Global Market for Enbrel 97 5.15.3.1 Enbrel’s Market by Geography 97 5.15.3.2 U.S. Sales of Enbrel 98 5.15.4 Global Market for Symponi 99 5.15.5 Global Market for Tysarbi 100 5.15.5.1 U.S. Market for Tysarbi 101 5.15.6 Global Market for Lantus 101 5.15.6.1 Lantus’ Market by Geography 102 5.15.6.2 U.S. Market for Lantus 103 5.15.7 Global Market for NovoRapid 103 5.15.7.1 Market for Novolog/Novorapid by Geography 104 5.15.7.2 U.S. Market for NovoRapid 105 5.15.8 Global Market for Victoza 105 5.15.9 Global Market for Levemir 107 5.15.9.1 U.S. Market for Levemir 108 5.15.10 Global Market for Humalog 108 5.15.10.1 Market for Humalog by Geography 110 5.15.11 Global Market for Neulasta 110 5.15.11.1 Neulasta’s Market by Geography 111 5.15.11.2 U.S. Market for Neulasta 112 5.15.12 Global Market for Privigen 112 5.15.13 Global Market for Perjeta 113 5.15.14 Global Market for Xgeva/Prolia 114 5.15.15 Global Market for Soliris 116 5.15.15.1 U.S. Market for Soliris 117 5.15.16 Global Market for Botox 117 5.15.17 Global Market for Lucentis 119 5.15.17.1 U.S. Market for Lucentis 120 5.15.18 Global Market for Eylea 120 5.15.19 Global Market for Avastin 122 5.15.19.1 U.S. Market for Avastin 123 5.15.20 Global Market for Rituxan 123 5.15.20.1 Rituxan’s Market by Geography 124 5.15.20.2 U.S. Market for Rituxan 125 5.15.21 Global Market for Revlimid 125 5.15.22 Global Market for Herceptin 127 5.15.22.1 Herceptin’s Market by Geography 127 5.15.21.2 U.S. Market for Herceptin 128 5.15.22 Global Market for Prenvar 13 129 5.15.22.1 U.S. Market for Prenvar 13 130 5.15.23 Global Market for Gardasil 130 5.15.24 Global Market for Fluzone/Varigrip 132 5.15.25 Global Market for Varivax 132 5.15.26 Global Market for Stelara 134 5.15.26.1 U.S. Market for Stelara 135 5.15.27 Global Market for Actemra 135 5.15.28 Global Market for Gammagard Liquid 136 5.16 The U.S. Biotech Landscape 138 5.16.1 Top U.S. Biotech Companies 138 5.16.1.1 Amgen 138 5.16.1.2 Gilead Sciences 139 About Author Bio:  I am working with a market research company which provides market research reports , custom research, company profiles, industry analysis, country reports , business reports, online databases and the report on Biologics and Biosimilars World Markets etc. Through our industry analysis you can identify opportunities, analyze the requirements of the customers and study the competition sector wise.

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