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What is Recurrent implantation failure? Recurrent implantation failure is a process that refers to a failure pregnancy after transfer of at least four healthy as well as good quality embryos in a minimum of three fresh or frozen cycles in a woman under the age of 40 years. When implantation failure occurs more than once with good quality embryos, then it is called recurrent implantation failure. It is not a simple condition as it is hard for doctors to know what causes it and what to do to fix it. It is a frustration situation for both patient and a doctor. According to a survey, it is estimated that approximately 10% of women seeking IVF treatment face this particular problem. Causes of Recurrent implantation failure: There are several reasons, which may cause recurrent implantation failure. Some may be as follows: 1. Quality of embryos: Quality of embryos is a major factor in IVF treatment. If embryos are of poor quality, then the possibility of successful implantation is reduced. A healthy and good quality embryo has the correct number of cells corresponding to the day of its development and day-5 embryos (Blastocysts) were graded according to expansion and quality of the inner cell mass and trophectoderm. 2. The Endometrium Factors: It is assumed that big fibroids, big size endometrial polyp may interfere with implantation and leads to recurrent implantation failure. 3. Hydrosalpinges: When the fallopian tube is filled with water or fluid then this condition is known as hydrosalpinges. Fluid from the fallopian tube enters in uterine cavity and this may lead to pregnancy failure. 4. Thrombophilia and Immunological Factors: The immune system of human body protects infections and abnormal process. The increase of uterine natural killer cells in woman leads to pregnancy failure. Treatment before Recurrent implantation failure occurs: In some cases if repeated failure occur during IVF, some possible treatment is done before prior to implantation. • Intravenous Immunoglobulin (IVIg): It is a medication, which is effective in treatment of implantation failure for those women who are experiencing implantation failure after IVF. • Intralipid (IL): It is also a treatment for RIF. It is useful for those patients who have abnormal Natural Killer cell level, and is usually administrated intravenously. It may alsoenhance implantation rate and help in maintenance of pregnancy. Other several things which are necessary to consider to prevent RIF include stress reduction, dietary changes, and acupuncture. These issues should be resolved after first cycle. Sumiran Hospital Ahmedabad is among best top ivf centres in india situated in Ahmedabad. To know more about best ivf center in Ahmedabad , male infertility treatment, ivf treatment cost, visit our website. Here you will find all solutions related to infertility.
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