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Cdc: multistate outbreak of shiga toxin-producing escherichia colio145 infections by 123wert sdfsf





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Cdc: multistate outbreak of shiga toxin-producing escherichia colio145 infections by
Article Posted: 01/04/2013
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Cdc: multistate outbreak of shiga toxin-producing escherichia colio145 infections


 
Business,Business News,Business Opportunities
Posted: June 11th, 2012 - 1:10pm Source: barfblog The U.S. Centers for Disease Control has issued an initial outbreakannouncement regarding the on-going E. coli O145 outbreak. • A total of 14 persons infected with the outbreak strain ofSTEC O145 infection have been identified in 6 states.



• The number of ill persons identified in each state is asfollows: Alabama (2), California (1), Florida (1), Georgia (5),Louisiana (4), and Tennessee (1). Three ill persons have been hospitalized; one death has beenreported in Louisiana. • Based on interviews conducted to date, a source for theseinfections has not been identified. If a specific source isidentified, public health officials will advise the public and takesteps to prevent additional illnesses. • Dates for patients' onset of illness range from April 15 toMay 12, 2012.



It has been approximately 4 weeks since the lastillness onset among reported cases. Although this indicates thatthis outbreak could be over, CDC continues to work with statepublic health officials to identify additional cases and the sourceof these STEC O145 infections. CDC is collaborating with public health officials in multiplestates to investigate a multistate outbreak of Shigatoxin-producing Escherichia coli serogroup O145 (STEC O145)infections. Public health investigators are using DNA"fingerprints" of E.



coli bacteria obtained throughdiagnostic testing with pulsed-field gel electrophoresis, or PFGE,to identify cases of illness that may be part of this outbreak.They are using data from PulseNet, the national subtyping networkmade up of state and local public health laboratories and federalfood regulatory laboratories that performs molecular surveillanceof foodborne infections. The type of bacteria responsible for this outbreak is among thosereferred to as Shiga toxin-producing E. coli or STEC. STEC bacteriaare grouped by serogroups (e.g., O157 or O145).



The STEC serogroupfound most commonly in U.S. patients is E. coli O157. Other E.



coliserogroups in the STEC group, including O145, are sometimes called"non-O157 STECs." Some types of STEC frequently causesevere disease, including bloody diarrhea and hemolytic uremicsyndrome (HUS) which is a type of kidney failure. Currently, thereare limited public health surveillance data on the occurrence ofnon-O157 STECs, including STEC O145; many STEC O145 infections maygo undiagnosed or unreported. Compared with STEC O157 infections,identification of non-O157 STEC infections is more complex. First,clinical laboratories must test stool samples for the presence ofShiga toxins. Then, the positive samples must be sent to publichealth laboratories to look for non-O157 STEC.



Clinicallaboratories typically cannot identify non-O157 STEC. The STEC O145PFGE pattern in this outbreak has not been seen in PulseNet before. A total of 14 persons infected with the outbreak strain of STECO145 infection have been identified in 6 states: Alabama (2),California (1), Florida (1), Georgia (5), Louisiana (4), andTennessee (1). Among persons for whom information is available,illness onset dates range from April 15, 2012 to May 12, 2012. Thetime from the beginning of a patient"s illness to theconfirmation that he or she was part of an outbreak is typicallyabout 2-3 weeks.



Please see the E. coli Outbreak Investigations:Timeline for Reporting Cases for more details. Ill persons range inage from 1 year to 79 years old, with a median age of 33 years old;79% are female. Three ill persons have been hospitalized; one deathhas been reported in Louisiana.



CDC initiated an investigation into this cluster of illnesses onMay 14, 2012. At that time, six ill persons had been reported toCDC PulseNet from two states during May 3, 2012 to May 9, 2012.Although the most recent report of an illness to CDC was on June 4,2012, their onset of illness occurred before May 10, 2012 and wasduring same period as other ill persons in this outbreak. It has been approximately 4 weeks since the last illness onsetamong reported cases. Although this indicates that the outbreakcould be over, CDC continues to work with state public healthofficials to identify additional cases and the source of these STECO145 infections. State public health officials have been interviewing ill persons toobtain information regarding foods they might have eaten and otherexposures in the week before illness.



Based on interviews of 10 illpersons to date, a source for these infections has not beenidentified. Preliminary results indicate that this strain of E. coli producesShiga toxin type 2 and is susceptible to all antibiotics tested. www.cdc.gov/ecoli/2012/O145-06-12/index.html.

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