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A study published in the May 9 issue of JAMA reveals that eating probiotic foods (live microorganisms), such asyogurt, reduces the risk of antibiotic-associated diarrhea, aprevalent side effect of antibiotic use. The researchers explained: "The use of antibiotics that disturb the gastrointestinal flora [microbes] is associatedwith clinical symptoms such as diarrhea , which occurs in as many as 30 percent of patients. Symptoms range from mild and self-limiting to severe, particularlyin Clostridium difficile infections, and antibiotic-associateddiarrhea (AAD) is an important reason for nonadherence withantibiotic treatment. Potentially, probiotics maintain or restore gut microecology(microbial ecology) during or after antibiotic treatment. There isan increasing interest in probiotic interventions, and evidence forthe effectiveness of probiotics in preventing or treating AAD isalso increasing." Susanne Hempel, Ph.D., of RAND Health, Santa Monica, Calif., andher team searched databases in order to identify randomizedcontrolled trials (RCTs) involving probiotic use (Lactobacillus,Bifidobacterium, Saccharomyces, Streptococcus, Enterococcus, and/orBacillus) for the prevention or treatment of AAD. In total, 82trials met inclusion criteria. The researchers found that most of the trials used eitherLactobacillus-based interventions alone or in conjunction withother genera (a subdivision of a family of organisms); strains werenot well documented. 63 of the 82 trials reported the number of participants randomizedto both treatment groups, as well as the number of participantswith diarrhea. Combined, the 63 trials included 11,811participants. The researchers found that participants who consumedprobiotics were 42% less likely to develop diarrhea thanparticipants assigned to a control group. According to theresearchers, the result was consistent across numerous subgroup andsensitivity analyses. The treatment effect equates to a numberneeded to treat of 13. The authors explained that the findings in the pooled resultsvaried significantly. In addition, they found that there was notenough evidence to determine if this association differssystematically by population, probiotic preparation, or antibioticcharacteristic. The researchers conclude: "In summary, our review found sufficient evidence to conclude thatadjunct probiotic administration is associated with a reduced riskof AAD. This generalized conclusion likely obscures heterogeneityin effectiveness among the patients, the antibiotics, and theprobiotic strains or blends. Future studies should assess these factors and explicitly assessthe possibility of adverse events to better refine ourunderstanding of the use of probiotics to prevent AAD." Written By Grace Rattue Copyright: Medical News Today Not to be reproduced without permission of Medical News Today Additional References Citations. I am an expert from refrigeratorreplacementpart.com, while we provides the quality product, such as China Refrigerant Filter Drier , China Tension Lock, Refrigerator Door Handle,and more.
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