Amazines Free Article Archive
www.amazines.com - Saturday, May 28, 2022
Read about the most recent changes and happenings at Amazines.com
Log into your account or register as a new author. Start submitting your articles right now!
Search our database for articles.
Subscribe to receive articles emailed straight to your email account. You may choose multiple categories.
View our newest articles submitted by our authors.
View our most top rated articles rated by our visitors.
* Please note that this is NOT the ARTICLE manager
Add a new EZINE, or manage your EZINE submission.
Add fresh, free web content to your site such as newest articles, web tools, and quotes with a single piece of code!
Home What's New? Submit/Manage Articles Latest Posts Top Rated Article Search
Google
Subscriptions Manage Ezines
CATEGORIES
 Article Archive
 Advertising (133514)
 Advice (161571)
 Affiliate Programs (34788)
 Art and Culture (73835)
 Automotive (145677)
 Blogs (75393)
 Boating (9851)
 Books (17221)
 Buddhism (4129)
 Business (1329944)
 Business News (426412)
 Business Opportunities (366444)
 Camping (10970)
 Career (72776)
 Christianity (15844)
 Collecting (11639)
 Communication (115069)
 Computers (241913)
 Construction (38921)
 Consumer (49947)
 Cooking (17078)
 Copywriting (6730)
 Crafts (18205)
 Cuisine (7547)
 Current Affairs (20307)
 Dating (45901)
 EBooks (19700)
 E-Commerce (48246)
 Education (185373)
 Electronics (83517)
 Email (6439)
 Entertainment (159836)
 Environment (28922)
 Ezine (3040)
 Ezine Publishing (5452)
 Ezine Sites (1550)
 Family & Parenting (110928)
 Fashion & Cosmetics (196538)
 Female Entrepreneurs (11851)
 Feng Shui (132)
 Finance & Investment (310503)
 Fitness (106442)
 Food & Beverages (63005)
 Free Web Resources (7939)
 Gambling (30225)
 Gardening (25192)
 Government (10512)
 Health (629869)
 Hinduism (2206)
 Hobbies (44078)
 Home Business (91593)
 Home Improvement (251123)
 Home Repair (46209)
 Humor (4717)
 Import - Export (5456)
 Insurance (45103)
 Interior Design (29588)
 International Property (3488)
 Internet (191001)
 Internet Marketing (146662)
 Investment (22855)
 Islam (1161)
 Judaism (1352)
 Law (80454)
 Link Popularity (4596)
 Manufacturing (20901)
 Marketing (99269)
 MLM (14140)
 Motivation (18232)
 Music (26996)
 New to the Internet (9496)
 Non-Profit Organizations (4048)
 Online Shopping (129726)
 Organizing (7809)
 Party Ideas (11853)
 Pets (38070)
 Poetry (2229)
 Press Release (12687)
 Public Speaking (5639)
 Publishing (7561)
 Quotes (2407)
 Real Estate (126595)
 Recreation & Leisure (95456)
 Relationships (87647)
 Research (16180)
 Sales (80345)
 Science & Technology (110280)
 Search Engines (23496)
 Self Improvement (153285)
 Seniors (6216)
 Sexuality (35996)
 Small Business (49286)
 Software (83017)
 Spiritual (23466)
 Sports (116146)
 Tax (7659)
 Telecommuting (34072)
 Travel & Tourism (308168)
 UK Property Investment (3122)
 Video Games (13382)
 Web Traffic (11760)
 Website Design (56875)
 Website Promotion (36614)
 World News (1000+)
 Writing (35833)
Author Spotlight
DESIGNPLUZ DIGITALAGENCY

Designpluz has steadily matured from a passionate graphics design start-up, into a full service digi...more
MARBLEPLUS AUSTRALIA

Marble Plus - Sydney & Brisbane's leaders in stone and marble tiles. We honour small and wholesale o...more
SANTOSH GUPTHA

Certified Medical coder with 42 certifications,15 years experience in Medical records coding, HIPAA,...more
HANVEY HUANG

I'm a Chief Operated Officer from KIMKOO Mattress machinery.The pen is mightier than the sword.so I ...more
JOHN WHARTON

img border="0" height="22" src="3.bp.blogspot.com/-lwbCHWyiaZE/UkU4PxcWj8I/AAAAAAAAAA0/QooVAHCHbx4/...more


Vaccine development may improve with advanced genetic screeningmethod - PL Light Fittings by fdhjkl rfghjtkl





Article Author Biography
Vaccine development may improve with advanced genetic screeningmethod - PL Light Fittings by
Article Posted: 01/28/2013
Article Views: 131
Articles Written: 2148
Word Count: 529
Article Votes: 0
AddThis Social Bookmark Button

Vaccine development may improve with advanced genetic screeningmethod - PL Light Fittings


 
Business,Business News,Business Opportunities
The advantage of this in vivo technique is that it offers a meansof rapidly screening entire genomes, with the results of the searchdisplaying desired immunogenic traits. The mode of entry ofvaccines designed in this way closely resembles the naturalinfection process of host cells - an improvement over liveattenuated vaccines. This promising approach has been used effectively to engineer avaccine against hepatitis and may provide a new avenue for the development of protectiveagents against pathogens that have thus far eluded traditionalvaccine efforts, including HIV and ebola. "We had developed a method for screening for protective subunitsagainst a specific disease," Sykes says. "However this type ofsafer vaccine design is notoriously less potent than the wholepathogen designs.

What we needed was a method to find generallyuseful vaccine components that would serve to enhance and controlimmunity." The group chose the pathogen parapoxvirus ovis (known as the Orfvirus) for the current set of experiments, in which expressionlibrary immunization techniques were used to screen for animmunogenic factor buried in the pathogen's genome. Parapoxvirus ovis causes a highly infectious disease known as Orf,which is prevalent in sheep and goats and may be transmittedcutaneously to humans handling these animals, causing pustularlesions and scabs. Once the group had sequenced the full genome of parapoxvirus, PCRwas used to amplify all the viral open reading frames, which codefor all of the viruse's proteins. Each ORF, comprising a library ofgenomic components, was compiled into a unique high throughputexpression construct, and these were randomly distributed intosub-library pools. These pools were directly delivered into sets ofmice for in vivo expression.

Functional testing for the activitydesired identified B2 as the immune cell accumulator. In further experiments, the team co-delivered B2L as an additive oradjuvant for an influenza gene vaccine, to see if it could improvesurvival rates in mice challenged with the influenza virus. Theco-immunized mice indeed displayed full protection againstinfluenza compared with 50 percent protection of the control group,immunized with influenza vaccine alone. In addition to infectious agents like Orf, non-infectious diseasesincluding cancer may be amenable to vaccine defense. Thus far however, thediscovery of tumor-specific antigens has been frustrating.

Oneapproach may lie in using non-specific immunogenic factors like B2. In the current study, two forms of cancer were investigated in amouse model, following the administering of B2 alone, in theabsence of a disease antigen. The experiments evaluated B2'sability to enhance survival and shrink tumor size. In the case ofan aggressive melanoma , tumor size was significantly reduced and survival rate improved.Administration of B2 to an infection induced by a breast cancer cell line also showed a modest but measureable reduction in tumorsize. With the growing popularity of sub-unit vaccines, the need arisesfor more effective adjuvants, which may be used to compensate forthe reduced immunogenicity of such vaccines compared with theirwhole-pathogen counterparts.

Techniques similar to those appliedhere to isolate and evaluate B2 could potentially permit thescreening of virtually any genome for any gene-encoded activitytestable in an organism. Additional References Citations.

We are high quality suppliers, our products such as PL Light Fittings , Motion Sensor Led Night Light Manufacturer for oversee buyer. To know more, please visits T5 Led Tube Lights.

Related Articles - PL Light Fittings, Motion Sensor Led Night Light Manufacturer,

Email this Article to a Friend!

Receive Articles like this one direct to your email box!
Subscribe for free today!

 Rate This Article  
Completely useless, should be removed from directory.
Minimal useful information.
Decent and informative.
Great article, very informative and helpful.
A 'Must Read'.

 

Do you Agree or Disagree? Have a Comment? POST IT!

 Reader Opinions 
Submit your comments and they will be posted here.
Make this comment or to the Author only:
Name:
Email:
*Your email will NOT be posted. This is for administrative purposes only.
Comments: *Your Comments WILL be posted to the AUTHOR ONLY if you select PRIVATE and to this PUBLIC PAGE if you select PUBLIC, so write accordingly.
 
Please enter the code in the image:



 Author Login 
LOGIN
Register for Author Account

 

Advertiser Login

 

ADVERTISE HERE NOW!
   Limited Time $60 Offer!
   90  Days-1.5 Million Views  

 

Great Paranormal Romance


STEPHEN BYE

Steve Bye is currently a fiction writer, who published his first novel, ‘Looking Forward Through The...more
LAURA JEEVES

At LeadGenerators, we specialise in content-led Online Marketing Strategies for our clients in the t...more
SHALINI MITTAL

A postgraduate in Fashion Technology. Shalini is a writer at heart! Writing for her is an expression...more
STEVERT MCKENZIE

Stevert Mckenzie, Travel Enthusiast. ...more
GENE MYERS

Author of four books and two screenplays; frequent magazine contributor. I have four other books "in...more
ALEX BELSEY

I am the editor of QUAY Magazine, a B2B publication based in the South West of the UK. I am also the...more
NEVIO GARDASANIC

Hello, my name is Nevio Gardasanic. If you want to go beyond being just a perpetual beginner at thin...more
SANJIB DAS

Sanjib Kumar Das is an Indian business enthusiast and entrepreneur who is motivated to help small an...more
AKSHAY CHOPRA

Akshay Chopra is an experienced certified personal trainer and the founder of WERSTUID. An organizat...more
TIM FAY

I am not a writer nor am I trying to become a writer. I am an average person with average intelligen...more

HomeLinksAbout UsContact UsTerms of UsePrivacy PolicyFAQResources
Copyright © 2022, All rights reserved.
Some pages may contain portions of text relating to certain topics obtained from wikipedia.org under the GNU FDL license