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TUESDAY, May 29 (HealthDay News) — Intensive control of bloodsugar levels reduces the risk of certain signs of kidney damageamong diabetics, new research indicates. However, the evidence did not show that intensive control lowersthe risk of actually developing severe kidney disease. The two signs of kidney damage that the study focused on areconditions known as microalbuminuria and macroalbuminuria. Theseare characterized by excessive levels of protein in the urine,usually resulting from damage to the filtering units of thekidneys, according to background information in the study publishedMay 28 in the Archives of Internal Medicine. But, the review of data from seven clinical trials that includedmore than 28,000 adult patients did not find conclusive evidencethat intensive blood-sugar control was related to a reduced risk ofserious kidney problems, including kidney failure or death fromkidney failure. "Our analysis demonstrates that, after 163,828 patient-yearsof follow-up in the seven studies examined, intensive glycemic[blood sugar] control lessens albuminuria," but there'snot enough data to say if that benefit extends to kidney disease orkidney failure, wrote Dr. Steven Coca, of Yale University, andcolleagues. This may mean that there's little point to beginningintensive blood-sugar control in the mid-stage of type 2 diabetesin an attempt to prevent kidney failure, they concluded. However, an expert not involved in the study says the studiesincluded in this meta-analysis were too short to assess howintensive blood-sugar control might affect the risk of kidneyfailure in patients with type 2 diabetes. "Although implementing intensive therapy is difficult andimposes burden and expense, all of the primary data continue tosupport its long-term benefit," Dr. David Nathan, ofMassachusetts General Hospital, wrote in an accompanying editorial. Another expert agreed. "I feel this [finding] is misleading since most of thestudies included in the analysis had relatively short durations of‘intensive' treatment and also fairly short durationsof follow-up," said Dr. Tracy Breen, director of diabetescare at North Shore-LIJ Health System in New Hyde Park, N.Y. She added that "microvascular complications often take manyyears to develop – any analysis that includes trials withless than 10 years of follow-up may not have the statistical powerto show difference in clinical events." More information The American Diabetes Association has more about tight diabetes control . – Robert Preidt SOURCE: Tracy Breen, M.D., director, diabetes care, North Shore-LIJHealth System, New Hyde Park, N.Y.; Archives of Internal Medicine , news release, May 28, 2012 Last Updated: May 29, 2012 Copyright 2012 HealthDay. All rights reserved. The e-commerce company in China offers quality products such as Mobile Drilling Rigs , China Hydraulic Crawler Crane, and more. For more , please visit Core Drilling Rig today!
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