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Furosemide is a diuretic which is an anthranilic acid derivative. furosemide tablets for oral administration contain furosemide as the active ingredient and the following inactive ingredients: lactose monohydrate NF, magnesium stearate NF, starch NF, talc USP, and colloidal silicon dioxide NF. Chemically, it is 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid. furosemide is available as white tablets for oral administration in dosage strengths of 20, 40 and 80 mg. Furosemide is a white to off-white odorless crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids. Name:Furosemide (Related Reference) EINECS:200-203-6 Molecular Formula:C12H11ClN2O5S CAS Registry Number:54-31-9 Synonyms:5-(aminosulfonyl)-4-chloro-2-((2-furanylmethyl)amino)benzoic acid; 4-chloro-n-furfuryl-5- sulfamoylanthranilic acid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid InChI:InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19) Appearance:white powder Molecular Weight:330.74414 Density:1.606 Boiling Point:582.1 °C at 760 mmHg Melting Point:220? Flash Point:305.9 °C Storage Temperature:2-8°C Solubility:Slightly soluble in water Biological Activity:Loop diuretic that inhibits the Na + /2Cl - /K + (NKCC) cotransporter. Also acts as a non-competitive antagonist at GABA A receptors with ~ 100-fold greater selectivity for a 6-containing receptors than a 1-containing receptors. Stability:Stable, but light sensitive, air sensitive and hygroscopic. Incompatible with strong oxidizing agents. Usage:Used as a diuretic
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