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Liposomes are vesicles filled with liquid and they can be used to deliver medicine to cells, for cancer treatment and other issues. The particles are artificially obtained from cell membranes. Even if the compounds are really small, their wonderful characteristics can make them very useful for people. Experts consider the spheres today among the best ways of transporting nutrients to cells through the mouth. Made from phospholipids, which are contained by membranes, liposomes can have two separate layers. The substance also contains cholesterol. A hematologist from Great Britain named Alec D. Bangham noticed the compounds in 1961 and they were used later in fields such as medicine, biochemistry and biology. The specialist mentioned that one part of a molecule from the substance was solvable in water and another was resistant. The discovery was made accidentally, when Bangham was performing some verification on the electronic microscope of his institute. The test was made by drying phospholipids with a negative stain. Pictures were created and these were the first evidence of the bilayer structure of human cell membranes. If there is a disruption in a membrane, phospholipids can reorganize in the form of spheres, no matter if they are monolayer, or bilayer. Dual versions are the type of compounds that scientists call liposomes and the single ones are called micelles. The substances are taken from the natural content of cell membranes, but this is made artificially. In a normal cell, the membrane has an external part that is soluble, for letting nutrients enter the cell. When it comes to size, two types of spheres exist: uni-lamellar and multi-lamellar. The substance is unique due to its special features: soluble and insoluble materials can be moved using it, it is a stable structure if is diluted, the double layer can be penetrated by molecules and it is has fluidity. The properties can change when factors like temperature, nearby molecules or ionic strength affect them. The best use of liposomes can be for drug encapsulation. Formulas based on the compound are the first nano-pharmaceuticals ever used. The term comes from the Greek language, in which "Lipos" means fat and "Somos" is body. In cases in which phospholipids are placed in water based solutions, the insoluble parts of molecules separate themselves from the fluid, just like vinegar does not mix with oil. With the use of encapsulation, ingesting Vitamin C and taking it directly to the cells has never been easier. According to some theories, liposomes can contain a few therapeutic agents. However, researchers have not yet been able to prove this is totally true. Theories say that a liver can see phospholipids like fat and release Vitamin C. Another assumption can be that cells take materials from the substance in order to fix their membranes and leaks can occur. The conclusion could be that liposomes can be great means of transporting different types of materials to human cells, as they were part of membranes before. Despite their microscopic size, the compounds can have multiple characteristics. Scientists say that there are healing properties involves, but there is no proof of this for now. We have all the detailed specifics about liposome manufacturing on our related homepage. Simply use this link to reach the main site at http://www.encapsula.com.
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Liposomes, liposome formulation, Liposome Manufacturing,
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