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"I think when most people think about diabetes-relatedillnesses, they think of heart disease or kidney failure, but notnecessarily cancer," said lead author Jorge Castillo, M.D., ahematologist/oncologist with The Miriam Hospital. "But whenyou consider that more than 19 million Americans have beendiagnosed with diabetes -- not to mention the millions more who areeither undiagnosed or will be diagnosed in the future -- a 20percent increased risk of blood cancer is quite significant." While diabetes has been previously associated with other types ofcancer, such as liver and pancreatic cancer, there have been fewconnections to blood cancers. Researchers are still unclear whatcauses the vast majority of these malignancies, which includecancers of the blood, bone marrow, and lymph nodes and affect morethan 100,000 Americans each year. Castillo and colleagues analyzed 26 previously published researcharticles on the association between type 2 diabetes -- the mostcommon form of the disease -- and the incidence of lymphoma,leukemia and myeloma. The meta-analysis included more than 17,000cases of type 2 diabetes and blood cancer worldwide. They concluded patients with type 2 diabetes have increased odds ofdeveloping leukemia, myeloma and non-Hodgkin lymphoma, as well as asubtype of non-Hodgkin lymphoma known as peripheral T-celllymphoma. They did not find any associations with Hodgkin lymphoma. Interestingly, researchers also say the odds of lymphoma, leukemiaand myeloma appear to differ depending on the geographic region ofthe original report. For example, the odds of non-Hodgkin lymphomawere higher in Asia and Europe, while there was an increasedleukemia risk in the United States and Asia. Although the study did not identify a cause for any of theseassociations, the findings suggest type 2 diabetes could beassociated with approximately five percent of all incidents ofleukemia, myeloma non-Hodgkin lymphoma. "It's important to remember that type 2 diabetes can, to somedegree, be prevented and controlled through lifestyle modification,such as diet and exercise," Castillo said. "So bypreventing the onset of type 2 diabetes, we could also preventblood cancer." The researchers say additional studies are needed to explain thepotential relationship between type 2 diabetes and blood cancers.In particular, Castillo believes future research should focus onthe role of behavioral factors like obesity, physical activity andsmoking, which have been linked to both diabetes and cancer. Research reported in this publication was supported by the NationalCenter for Research Resources of the National Institutes of Healthunder award number UL1RR025752, the National Center for AdvancingTranslational Sciences and The Marilyn Fishman Grant for DiabetesResearch from the Endocrine Fellows Foundation. Study co-authorsinclude Nihkil Mull, M.D., John L. Reagan, M.D., and Saed Nemr,M.D., from The Miriam Hospital and Joanna Mitri, M.D., from TuftsMedical Center. The e-commerce company in China offers quality products such as Wooden Display Stands , China Kids Play Rug, and more. For more , please visit Acrylic Display Holders today!
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