Azithromycin is used to treat a wide variety of bacterial infections. It is a macrolide-type antibiotic. It works by stopping the growth of bacteria. This medication will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Azithromycin is used to treat or prevent certain bacterial infections, most often those causing middle ear infections, strep throat, pneumonia, typhoid, bronchitis and sinusitis. In recent years, it has been used primarily to prevent bacterial infections in infants and those with weaker immune systems. It is also effective against certain sexually transmitted infections, such as nongonococcal urethritis, chlamydia, and cervicitis. Recent studies have indicated it also to be effective against late-onset asthma, but these findings are controversial and not widely accepted. Name:Azithromycin Molecular Formula:C38H72N2O12 CAS Registry Number:83905-01-5 Appearance:white crystalline powder Molecular Weight:748.99 Density:1.18 g/cm3 Boiling Point:822.1 °C at 760 mmHg Melting Point:113-115? Flash Point:451 °C Refractive index:1.536 Solubility: Insoluble Hazard Codes: Xi RTECS : RN6960000 Hazardous Substances Data: 83905-01-5 Mechanism of action:Azithromycin prevents bacteria from growing by interfering with their protein synthesis. It binds to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA. Nucleic acid synthesis is not affected. Biological Activity: Macrolide antibiotic. Inhibits 50S ribosomal subunit formation and elongation at transpeptidation step in gram-positive and gram-negative organisms. Orally active with improved pharmacokinetics over erythromycin in mouse models. Stability: Stable. Incompatible with strong oxidizing agents. Usage: Semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial
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