Lyrica is a drug used to treat pain caused byneurologic diseases such as postherpetic neuralgas well as seizures. It also is used for treating fibromyalgia. |
Mechanism of action: It binds to calcium channels on nerves and may modify the release of neurotransmitters (chemicals that nerves use to communicate with each other). Reducing communication between nerves may contribute to it's effect on pain and seizures. Indications : To Control over neuropathic discomfort connected with diabetic peripheral neuropathy
- Management of post herpetic neuralgia
- Adjunctive therapy for adult patients with partial onset seizures
- Management of fibromyalgia syndrome
- Management of neuropathic discomfort connected with spinal-cord injuries
Dosage: Take this medication by mouth as usually 2 to 3 times a day with or without food.
DOSING This drug may be taken with or without food. The initial dose for neuropathic pain is 50 mg three times a day (150 mg/day). The dose may be increased to a maximum dose of 100 mg 3 times daily (300 mg/day) after one week.
The recommended dose for post herpetic neuralgia is 75-150 mg twice daily or 50-100 mg three times daily. Begin dosing at 75 mg two times a day or 50 mg three times a day (150 mg/day). The dose may be increased to 100 mg 3 times daily (300 mg/day) after one week. The recommended dose for treating seizures is 150-600 mg/day divided into 2 or 3 doses, starting at 150 mg daily and increasing based on response and tolerability. Fibromyalgia is treated with 300-450 mg/day in 2 or 3 divided doses.
Lyrica can rapidly reduce discomfort, improve sleep, which help many people with fibromyalgia syndrome function better and return to their daily programs. Additionally, it considerably reduces discomfort after taking Lyrica for just 1 week.
DRUG INTERACTIONS: Alcohol and drugs that cause sedation may increase the sedative effects of this drug. Pioglitazone and rosiglitazone cause weight gain, fluid retention and possibly heart failure. Therefore, combining pregabalin with these drugs may increase the occurrence of weight gain and fluid retention.
SIDE EFFECTS: The most common side effects are dizziness, drowsiness, dry mouth, edema (accumulation of fluid), blurred vision, weight gain, and difficulty concentrating.
Precaution: Stop using this medicine if you have swelling of the face, eyes, lips, gums, or tongue, or problems with swallowing or breathing. You may be having a severe allergic reaction or a condition called angioedema. It may cause blurred vision, double vision, clumsiness, unsteadiness, dizziness, drowsiness, or trouble with thinking.
STORAGE: This drug should be stored at room temperature, between 15-30 0C (59-86 F).
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