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Due to its unique molecular structure and physicochemical properties, hyaluronic acid shows a variety of important physiological functions in the body. For example, lubricate joints, regulate the permeability of the blood vessel wall, regulate protein, water electrolyte diffusion and operation, promote wound healing and so on. More importantly, hyaluronic acid has a special role in water conservation, which is the best moisturizing substance found in nature, and known as an ideal natural moisturizing factor. Its hyaluronic molecules can carry more than 500 times of water, so it is widely used in cosmetics. Hyaluronic acid is a multifunctional matrix, widely distributed in the human body. Of which the skin also contains a large amount of hyaluronic acid. The process of human skin maturation and aging also changed with hyaluronic acid content and metabolism, it can improve skin nutrition metabolism, make the skin soft, smooth, remove wrinkles, increase elasticity and prevent aging. Used in conjunction with other nutrients, may help to achieve the desired effect of promoting nutrient absorption. Hyaluronic acid itself has a negative charge, present in most of the soft tissues in the animal body. Its aqueous solution is viscoelastic fluid, filled in the space between cells and collagen fibers and covering in some skin tissue. In animals, its main function is to protect and lubricate cells, regulate the cell movement in this viscoelastic substrate, stable the collagen network structure and protect it from mechanical damage. Hyaluronic acid is widely distributed in the body connective tissues, almost in the form of pure state exists in the vitreous, joint cavity. The hyaluronic acid in the skin plays an important role in the epidermis metabolism of the human body. The hyaluronic acid destruction or disorder in the body can cause disease. The hyaluronic acid content reduction or damage in the skin can cause skin dehydration, wrinkles and loss of elasticity, makes skin aging. Thus, hyaluronic acid is also known as anti-aging factor. Hyaluronic acid is one of the major matrix components of human skin epidermis and dermis. Its physiological function is to allow water entering the cells gap, and combined with proteins to form a protein gel, stick the cells together, play the role of normal cell metabolism, have the effects that keep cells water, protect cells from pathogens violations, accelerated to recover skin tissue, improve wound healing regenerative capacity, reduce scarring, enhance immunity, etc. In pharmaceutical raw materials aspects, hyaluronic acid used as non-steroidal anti-inflammatory drugs, and auxiliary drugs on arthritis treatment, ophthalmology, cardiac surgery, has a unique effect in the treatment of scald, burns, frostbite, artificial skin, etc. By the influence of people grow older and the factors of nutrition, sunshine, environment and so on, the body's ability to synthesize hyaluronic acid decreased, the content of hyaluronic acid in the skin will be gradually reduced, human in embryo period has the highest concentrations of hyaluronic acid, and gradually decreased after birth. If positioning the relative content of hyaluronic acid to 100% in 20 years old people, then the 30,50,60 age will respectively decrease to 65%, 45%, 25%. When hyaluronic acid in the skin below a certain level, the water content of the skin surface will be gradually reduced, causes the stratum corneum aging, the skin becomes rough, appears wrinkles, loss of elasticity, looks senility, this phenomenon generally occurs after the age of 25. This is also one of the reasons that the gap between the elderly and children's skin. While the destruction of hyaluronic acid in the skin is related to UV, so people who were long-term engaged in field work, highland life have very rough skin, outdoors operations staff' compared with indoors officer, their skin also look more rough. Article Source:http://www.cospcn.com
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