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April 1, the National "Eleventh Five-Year" science and technology support project "Integrated Control of hypertension" in Beijing. The study will be through large-scale multi-center clinical trial, an integrated intervention in patients with hypertension, of hypertensive patients for our comprehensive treatment programs. This project will involve more than 150 clinical centers in the country and more than 13,000 patients with hypertension, the time will be over 5 years. Discussion group leader, the Chinese Academy of Medical Sciences Professor Wang Wen Fu Wai Hospital Research Institute focuses on the technical difficulties to be solved. You think high blood pressure what is most annoying? Long-term medication Life too taboo Hard to prevent cardio-cerebral vascular accident Complications Question, problem How to avoid self-damage kills 10 000 3000? Hypertension medication to life, but about half of patients not taking the law on time and volume, and even their own withdrawal, causing disease to develop. Cause patients to adhere to treatment because of course a lot, but Drugs Expensive and cause side effects of drugs decrease the quality of life is an important reason. For example, converting enzyme inhibitor antihypertensive effect than good things, but also can reverse left ventricular hypertrophy, kidney protection, improvement of insulin resistance on glucose and lipid metabolism had no adverse effects, and allows patients after myocardial infarction, heart failure patients improvement of heart function, recurrent myocardial infarction reduced mortality. But severe cough is a common side effect of the drug, as were the main reason for discontinuation. There are long-term use of drugs can cause excessive potassium loss, and some drugs can lead to impotence. Therefore, a more safe and effective development of new drugs is an urgent task. How to use the minimum dosage to achieve maximum effect? Hypertension is progressive cardiovascular syndrome, which damages the object is the heart, brain, kidneys and other organs of the body's most important, medically known as hypertension target organ. With the progression of the disease, high blood pressure will not only destroy the target organ, but also lead to kidney failure, heart disorders, atherosclerosis, stroke, sudden death and so on. Of hypertension in China in the past often focused on solving a single blood pressure problems, since the rate of lipid lowering therapy in China is still less than 10%, standardized non-drug therapy has never been seriously undertaken. If a joint blood pressure, lipid lowering and lifestyle intervention such as a multi-pronged comprehensive prevention programs, the extent to which patients can reduce the incidence of cardio-cerebral vascular accident? How to use the smallest dose to achieve maximum therapeutic effect? These still far from conclusion. How the program for individual choice buck? Recent years, the treatment of hypertension has been developed to compare a single drug plan comparison. Clinical practice shows that 2 / 3 of hypertensive patients need two or more antihypertensive drugs to blood pressure compliance. Combination therapy is an effective antihypertensive compliance measures, which have gradually become the consensus of the medical profession. But there were individual differences in drug side effects and drug resistance are different, the same does not apply to patients with hypertension are often the same step-down program. Current drugs more effective treatment of hypertension, but the efficacy of many drugs in combination therapy has no medical evidence to be evidence-based. Such as: Calcium channel blockers and diuretics are known combination, can further reduce the risk of stroke; new antihypertensive angiotensin receptor antagonist (ARB) to reduce cardiovascular and cerebrovascular events, and has a protective effect on the kidney. However, calcium antagonists and ARB combination, whether the superior efficacy of calcium antagonist and diuretic efficacy of combination? The possibility of further reduction of cardiovascular events? Have to be studied. Total blood Cholesterol Levels may be associated with cerebral hemorrhage? I am an expert from trk.cc, while we provides the quality product, such as Automobile Tracking Devices Manufacturer , China GPS Pet Locator, GPS Pet Locator,and more.
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