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Li bao and more anti-cancer drugs and then "upgrade" by zyzy wang





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Li bao and more anti-cancer drugs and then "upgrade" by
Article Posted: 06/22/2011
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Li bao and more anti-cancer drugs and then "upgrade"


 
Business,Business News,Business Opportunities
Chemotherapy heal as one of the 3 tumors, carnivals an irreplaceable effect. Among them, doxorubicin is the most widely acclimatized chemotherapy drugs, its breast cancer, gynecological cancer, Hepatic carcinoma , Lung Cancer , Lymphoma, multiple myeloma, intellectual and neck cancer, mild tissue sarcoma and so has a very nice therapeutic effect, unfortunately, the prescription surgery within the counselling of patients at the replicate instant shall initiate cardiac toxicity, hair give upward and surplus edge effects, serious impact upwards towards the top on the exists of patients quality.



However, the Shanghai Fudan-Zhangjiang Bio Medicine Co., Ltd., China's introductory unaligned conception ADM "missile"?? PEG-based liposome doxorubicin (Li Bao and more) can be exerted within the direction of resolve shortcomings of traditional doxorubicin, which is the contemporary chemotherapy drugs, taller formulations , presently obtainable as a breast cancer, Lymphoma Etc. Cancer First-line chemotherapy, and herald further escalation of the Chinese anticancer drugs.



Former Chinese Cancer Society Clinical Oncology, the spokeswoman collaboration of the Executive Committee chairman, remarked Ma Jun, Li Bao and some embraces the most gained engineering concealed liposomes tremendously wrote the existing current people of anti-cancer chemotherapy prescription medicines dynamics is a very pledging innovative chemotherapy drugs, can be manoeuvered within clinical breast cancer, ovarian cancer, lymphoma, multiple myeloma, leukemia, stomach, liver, silken tissue sarcoma, governor and neck malignant contamination and a allotment else configurations of cancer.



In malignant pollution therapy, patients routinely perceive a allotment of heart because of agonizing toxicity, vomiting, nausea, hair forfeit toxicity, chemotherapy had towards final outlook halfway, tremendously instilled the cure and overall survival, a lot Patients did not even go within the direction of the vintage disease, Adds New disease, one time clinical witnessing of patients within the medication a minority years, a figure of granddaughter afterwards harsh dilated cardiomyopathy and extra heart diseases. Therefore, clinicians within the choice of as shortly as such pharmaceuticals are within wrapping very cautious, towards prevent larger impairment inside the direction of patients.



Liposomal doxorubicin (where several than Celebrex) may deter the emergence of is dismayed draw stick close medicine and patients because the prescription surgery doxorubicin inside the contemporary prescription medicines on the re-upgrade, edited the transmission of drug. Typically, the pharmaceuticals move into the human body is not intentional, but quite similarly disseminated within all tissue sectors of the body, so inside attachment within the therapy of diseases, prescription medicines furthermore injuries routine tissue.



Liposomal doxorubicin is the utilisation of liposome technology, the 100nm doxorubicin bundled circle the microcapsules in a structure, its policy role is to interpret effectiveness attenuated the operation of editing the prescription medicine in the body distribution, boost in tumor tissue distribution, weaken the benchmark tissue distribution, and thereafter to not individually slaughter tumor flats without harming routine tissue, dampening edge upshots of customary chemotherapy drugs.



Especially every time the drug retires into the human body is not again the standard boat wall, it unable to inject into common tissues, consequently dampening the introductory cardiac toxicity, hair loss and other sombre edge effects, has "not sad, not hair loss" characteristics. However, these liposome particles in the vicinity of body-fluid ships via malignant tumors, because these life-force vessels, blood pan wall, a lot sieve-like holes, liposome particles can carry on to leak over the holes to the tumor tissue, tumor tissue in localized directing at clustering, in order that the restricted drug engrossment in tumor tissue up to routine tissue concentration of several than 60 times, vastly elevated the antitumor activity.



According to clinical research, in the remedy of great cancers, with a PEG of liposome technology can be manufactured in numerous than commonplace Paula doxorubicin promotion more than 50%, wherever the edge impressions merely overall doxorubicin factors of 10%.



Of the China Society of Clinical Oncology Cancer collaborative guru Shu-Kui Qin, executives of the Executive Committee for broad years underneath Paula's result is: the main tumor aiming at properties with chemotherapy drugs, can unquestionably discern the site of tumor tissue endures , directed at attacks, with escalated efficacy without editing the common tissue function, can greatly lessen or leaving the conventional chemotherapy drugs is strong to nailed cardiac toxicity, alopecia, neurotoxicity and other policy boundary effects, altered patient quality of life, sweep chemotherapy .

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