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Fluorine-containing organic intermediates into the new drug market an important foundation by sgbvdf asga





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Fluorine-containing organic intermediates into the new drug market an important foundation by
Article Posted: 06/25/2011
Article Views: 132
Articles Written: 2044
Word Count: 862
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Fluorine-containing organic intermediates into the new drug market an important foundation


 
Business,Business News,Business Opportunities
In modern years, as within the chemical, Pharmacy And agricultural sectors are marvellous entry of organic fluoride Intermediate Is slowly steering marvellous rises potential. In the drug sector, a discrepancy of medicinal aggregate within the synthesis system lacks towards consumption fluorine-containing organic Intermediate Therefore, the fluorine-containing organic intermediates cornering into some important, R & D achievements are gradually active.



Becoming gradually esteemed Fluorine-containing organic intermediates adapted inside the drug commerce API Production. Trends advocate that the demonstration of prescription nurses aggregates inside fluorine-containing aliphatic or aromatic organic intermediate look for is becoming increasingly everywhere inside the prescription nurses refining the proportion of species.



Organic fluorine combinations has great stability, Physiological Activity of water dissolvable and sulfur, can be turned Saving Son, lipophilicity and additional parameters, a lot fluorine-containing pharmaceuticals exercised within the system of a quite let down budget of let down toxicity, high efficacy, metabolism, and enthusiastic characteristics of the pharmacodynamics of the drug and pharmacokinetic properties of esteemed impact. As the very satisfying method of fluorinated drugs, therefore, endorsed the proliferation of fluorine-containing drugs, organic intermediates representing fluorine inside the direction of widen living and international markets.



At this stage, the primary entry of fluorine-containing organic intermediates within the fluoroquinolone market prospect Ketone Drugs. Fluoroquinolones are the forenoon 70s of last century years created a recent class of anti-infectives, anti-fungal spectrum broader, fewer side impacts and affordable, within modern years, fast springs of antibiotic category. Such as ciprofloxacin, norfloxacin, moxifloxacin, levofloxacin, ofloxacin, are inflicted via employing fluorinated intermediates.



Beachhead future market lot Fluorinated aromatic substances inside the international market, the Italian Miteni company, Rhodia Inc. and Belgium SolvayFluor is several inflamed intermediates.



According inside the direction of forecasts, the worldwide prescription doctors commerce is inside a interval of fast growth, driven via request for fluorine-containing intermediates are within taping expanding, and its anticipations impressive. In fact, commerce advisors and advisors possess all individuals held the view: the drawing finish years, one third of the fresh drug shall be built embraced upward onto fluorine chemistry.



At this stage, China and European continent are energetically entangled within the demonstration of fluorine-containing intermediates, India, whoever in uniting resigned, subsequent being firmly follow. It is important that whilst the presentation of fluorine-containing intermediates Indian industries are not many, but the gets top of organic fluorine intermediates market in India is a pair other some organic intermediates rush. A movement has originated in India?? Some Indian Dye Intermediates across the integration of organic fluorine intermediates were mostly embroiled in the production.



At the neat level, India has a eager advantage in the field of organic fluorine intermediates own been urging a class of well-trained scientists, these favorable requirements shall endow India in the direction of become a China and European continents is a enthusiastic contender and will assist India's leaps the enterprising independently established out fluorinated intermediates and APIs, towards give in the direction of the household and international markets.



Currently in the international market, China's manufacturers are energetically entangled in the demonstration of aromatic fluorine-containing intermediates, for example fluorinated benzene, fluoroaniline, F Toluene And so on. In joining towards the vast supply of servant majority drug market in China will be a numerous diagram of these intermediates exported to other countries. Industry analysts predict, handed the degree of demonstration in China and has the abilities to mass demonstration of these intermediates, the coming years, China's item of these product unable to be shaken dominance.



Domestic R & D in the ascendant



Country in the expansion of fluorine-containing organic intermediates on the frame with aspect raw materials, are now shaped a sure scale of industry. National Organic Fluorine chemical products is approximated to possessed entire every year sales of plural than ten billion yuan, every year sales salary of 1.5 billion or numerous enterprises owned four, fluorinated aromatic and aromatic heterocyclic sequence Pesticide And Pharmaceutical Intermediates More than 100 multiplies of products, annual incomes of several than 60,000 tons.



Domestic growth of fluorine-containing drug intermediates, bulk raw portions are the basis of the initiating chemicals such as nitro-chlorobenzene, dichlorobenzene, etc., which are based on the supply of chemical raw members in China wealthy and good quality; In addition, China Fluorite Abundant, based fluoride sectors stronger. Can be remarked that the commerce of organic fluorine industry in China is a very favorable material advantages. With the advantage, China since the 70s the commerce of organic fluorine intermediates and fine chemicals to the 90's, my fluorochemicals many robust speed is present, China has become the highest products resulted of fluorine-containing drugs and intermediates one of the countries, more than 80% of the sell goods give of fluorine-containing intermediates.



Present, China has taller and been put into mass production mainly quinolones norfloxacin, ciprofloxacin, ofloxacin, of which the norfloxacin, ciprofloxacin, oxygen fluoride Star triggerred the utmost assignment of sand, approximate Fluoroquinolone servant output 98%.

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