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Not long ago, "Nature? Medicine" magazine's senior editor Claire? Thomas interviewed 25 AIDS Research the authority of the researchers hope to extract from their brainstorming out the answer. But the bear market is not made by the end of the iron law still in force? Their common conclusion that "an effective HIV vaccine appears in the next 10 to 15 years will not be found." 9 24, the U.S. and Thai researchers announced that they Cooperation Development of a test AIDS Human vaccine can reduce the risk of HIV infection 31.2%. This is the first time with the immune effect of the human AIDS vaccine. Since HIV (hereinafter referred to as HIV) in 1983 by the French Pasteur Institute virologist, 2008 Nobel Prize in Physiology or Medicine Prize winner Luc? Montagnier isolated the first time after dealing with the diseases of the journey, people are always optimistic and pessimistic Wandering between two poles. In 1984, then-Minister of Health and Human Services Margaret? Hai Gele has declared that you can have a vaccine within two years listed, but now, in the successive failure of combat, the United States National Institute of Allergy and infectious Disease Research Institute Anthony? Fauci said pessimistically, although not yet to give up, but we may never be an effective HIV vaccine. Vaccine clinical trials in the nowadays have failed the backdrop, the U.S. military and the Thai Ministry of Public Health conducted a joint study of the progress of the new vaccine appears to seek a way out of line we see the dawn. Combination vaccine is really effective? The study, called RV144 from October 2003 started, the number of participants Yu Wan is the only HIV-vaccine clinical trials. Scientists in Thailand were selected by 1.6 thousand aged between 18 to 30 years old, HIV testing was negative and similar infection rates and ordinary people participated in the study volunteers were divided into vaccine and placebo groups. According to the latest research results showed that the vaccine in 8197 volunteers, 51 were infected with the HIV drug, which consists of the placebo group of 8198 people, 74 people infected, which means that the risk of infection vaccine group decreased 31.2%. And scientists are confident that this difference was statistically significant, is not accidental factors. This new vaccine should actually be classified as the scope of the combined vaccine, which is precisely the two components had failed "criminal record" of the old vaccine?? ALVAC and AIDS VAX. The former is a recombinant canarypox virus vector vaccine contains three HIV genes, its designed to be not to prevent infection, but is responsible for stimulating the immune system, through cell-mediated immune responses, so that the body can take precautions, and HIV can play in the face of strong resistance when the role, which contains a recombinant HIV surface protein gp120, which plays the role of the hand assists and played strong immune response, efforts to strengthen the role of attack. 2003, the beginning of this vaccine in Thailand I and II clinical trials of experimental results show that healthy subjects participated in the experiment no significant Adverse reactions , No one infection during the experiment HIV. Subsequent assessment that the vaccine has a good drug tolerance and produce a vaccine. Time to 2006, formally approved the vaccine into the randomized, double-blind phase III clinical trials, vaccination to take immune - enhancing (prime-boost) strategy. The immunized group trial in healthy volunteers after the start of the first 0,1,3,6-month injection of ALVAC vaccine, at 3 and 6 months vaccination AIDSVAX. In the next three years once every 6 months HIV test. Soon as he announced the results of clinical trials, immediately stirred up great controversy in the industry. Disclosure of information on the current view of many urgent questions to answer?? Against different HIV for different people, whether the new vaccine has the same immunity effects? New vaccine effective immunization of a long period? Why only show the new vaccine very limited immunogenicity?? still no clear answer. In addition to already infected people, even if vaccinated, the immune system is still facing the risk of serious damage. WHO and UNAIDS in the cautious optimism I also said that the existing test results alone, not yet approved the vaccine into production, it can not be used to replace the existing HIV prevention measures. All these unknowns and shortcomings so that people excitedly, could not help but dream to conquer HIV put a big question mark. The e-commerce company in China offers quality products such as China LED Underwater Light , LED Cabinet Light , and more. For more , please visit Roadway Lighting today!
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