2. Film Packaging In China to promote the application of the main Chinese medicine granules, powder, powder bags and other plastic composite membrane, the major developments in several varieties. (1) bi-oriented polypropylene (BOPP) film, which has good transparency, heat resistance and barrier properties, for the package bag's outer layer. The BOPP film and the sealing of a good LD-PEEVA, EEA, EAA, or with aluminum foil, can greatly increase the stiffness and the composite membrane mechanical properties. Such as BOPP film coated with moisture and good barrier PVDC, can greatly improve its barrier properties. (2) tape casting polypropylene film (CPP). It has good heat sealing, multi-package bag inner for vacuum after aluminum can and BOPP, PET, OPA, PT complex. (3) polyester film (PET). It has excellent mechanical strength and rigidity, heat resistance chemical resistance, transparency, gloss, water vapor and oxygen transmission rate less, with especially good taste of Paul, the other film that is unparalleled . (4), polyvinylidene chloride film (PVDC). It is the best film of barrier properties, except for pharmaceutical packaging, but also widely used in packaging other products such as meat products, pastries and tea.
Coating is a pharmacy one of the most commonly used technique, which involves physical chemistry, chemical engineering, fluid mechanics, polymer science and other disciplines. In recent decades, with new materials, new technologies, the continuous production of new machinery, coating technology has developed rapidly, forming a more complete set of theoretical and operational experience in the pharmacy plays an important role. Generally used in solid form coating agents, according to different coating materials can be divided into powder coating, pellet coating, coated pellets, coated tablets, capsules coating; under different coating materials into sugar coating, Semi-film coating, film coating (in a wide range of polymer materials, ranging from enteric coating), special material coating (such as stearic acid, paraffin, polysaccharides); based coating technology were divided into spray coating, dipping coating, dry compression coating, electrostatic coating, laminating coating. Among the most widely used spray coating, the principle is coated droplets of liquid sprayed into a mist covering the material "powder, granule, tablet) surface, and the rapid formation of clothes drying layer; purpose under the coating divided into water-soluble coating, stomach-soluble coating, an insoluble coating, release coating, enteric coating.
As film-forming agent and auxiliary additives are most excellent physical and chemical properties of polymer materials, so film-coated tablets not only moisture, light, taste masking, wear, and easy to mildew, easy to collapse, greatly improved drug dissolution, bioavailability and drug period, the drug can greatly expand the national and regional sales, effectively promoted the export of drugs, especially in proprietary Chinese medicines. Film quality clothing much less than the icing, the drug core weight in case, after the pill pack weight, which weighs 10 times more than the earlier ones. Therefore, the film production of clothing not only save a lot in accessories, but also in packaging, storage, transportation, etc. are taking more savings and convenience. Now a lot of film-forming materials and accessories, all made of carefully designed to suit the different characteristics of the film to change the drug core of the release location and release characteristics of drugs. In addition to Stomach film now, enteric film, there are mouth dissolving film (tablets), release film, release film, complex film, and the latest multi-layer, microporous membrane, osmotic pump coating, etc. This efficacy can be greatly increased.
Now developed a new product formulations commonly used coating film coating, film coating formulation of the basic components, including film-forming agent (coating material), solvents, plasticizers, coloring agents, also can be added porogen insoluble fillers. The commonly used water-soluble film coating materials include hydroxypropyl methyl cellulose (HPMC), hydroxypropyl cellulose (HPC), polyethylene glycol (PEG), polyethylene than slightly flavanone (PVP), Enteric enteric materials include acrylic resins, hydroxypropyl methyl cellulose phthalate (HPMCP), cellulose acetate phthalate (CAP), shellac, insoluble materials include ethyl cellulose ( EC), corn protein.
3. Can take medicine packing Such packaging materials mainly capsules, micro-capsules and accessories. Also known as soft elastic capsule capsule, its flexibility depends on the capsule shell of gelatin, plasticizer and water, the three EE patients. The earliest soft capsules of vitamin A, D capsule. Because of the soft capsule formulation bioavailability is good, sealing, security, pharmaceutical stability, dose accuracy, good appearance, portable and easy to use and so on, so more and more consumers, domestic and international market prospect and huge development potential.
According to an estimated global annual consumption in recent years, various capsule up to one trillion dollars, its total sales of pharmaceutical preparations the total amount of about 1 / 4. The world on research and development of the capsule attached great importance to the soft capsule preparation is constantly evolving. The United States is the world's largest manufacturer of soft gelatin capsules, in 10 countries with 20 subsidiaries worldwide sales of approximately 70% of the soft capsule market. Sales of large companies are Germany and the UK. The current global sales of soft capsule about 400 million U.S. dollars, of which a larger proportion of nourishing food, when up to 70%, and in developed countries have broad prospects.
Recent years, the production of soft capsules and development of more importance, but also made some progress, the production scope of Western medicine from the simple to the development of proprietary Chinese medicine formulations have been nine in the pharmaceutical production of soft capsules put in traditional Chinese medicine preparation market, manufacturers have developed a nourishing food soft capsules. The domestic market from the current point of view, the soft capsule preparation in terms of variety, quantity, intended purpose, appearance and so far failed to meet market needs, the development of space is also huge.
4. Blister Packaging Tablet is the most diversified, best-selling pharmaceutical dosage forms. Bulk glass is quickly out of the field, replaced by plastic bottles and aluminum-plastic blister packs.
Most common blister packaging is made from polyvinyl chloride film (PVC), polyvinylidene chloride (PVDC) and compound double aluminum (CFF) made. PVC film has excellent compatibility and easy molding and sealing, low cost, but the moisture barrier is relatively low. CFF has a good moisture barrier, but easy to distort and not see the inside of medicine, therefore, rarely used types of pharmaceutical pills. With the packaging technology and the rapid development of the pharmaceutical industry, PVC and PVDC some shortcomings continue to show weaknesses. Such as PVC, I am a professional writer from China Auto Suppliers, which contains a great deal of information about noah's ark toy , electronic personal organizer, welcome to visit!
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