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What is Hypertension? Everyone talks about hypertension. Many individuals, groups, communities, health Organizations and other bodies have shown concern and even written about Hypertension. Statistics shows that approximately 1 billion people worldwide have high blood pressure and this number is expected to increase to 1.56 billion people by the year 2025. That translates to about 1 out of every 4 Adults being afflicted with hypertension. In fact in the United States, recent estimates show that nearly one in three U.S Adults has high blood pressure and because there are no symptoms, nearly one-third of these people don't know they have it. Unfortunately, many may have it for years without even knowing. With this alarming statistics, you will not hesitate to agree with me that there is a call for concern for individuals and groups to treat this case with all seriousness. Captopril (rINN) is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of Hypertension and some types of congestive heart failure. Captopril was the first ACE inhibitor developed and was considered a breakthrough both because of its novel mechanism of action and also because of the revolutionary development process. Captopril is commonly marketed by Bristol-Myers Squibb under the trade name Capoten. Captopril was developed in 1975 by three researchers at the U.S. drug company Squibb (now Bristol-Myers Squibb): Miguel Ondetti, Bernard Rubin and David Cushman. Squibb filed for U.S. patent protection on the drug in February 1976 and U.S. Patent 4,046,889 was granted in September 1977. What should I discuss with my doctor before taking captopril? If you have certain conditions, you may need a dose adjustment or special tests to safely take captopril. Before you take this medication, tell your doctor if you have: kidney disease (or if you are on dialysis),liver disease, heart disease or congestive heart failure,diabetes, or a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis. FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Captopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Captopril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. What are the possible side effects of captopril? Get emergency medical help if you have any of these signs of an allergic reaction to captopril: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects: feeling light-headed, fainting, urinating more or less than usual, or not at all, fever, chills, body aches, flu symptoms, pale skin, easy bruising or bleeding, fast, pounding, or uneven heartbeats, chest pain or swelling, rapid weight gain. Less serious captopril side effects may include: cough,loss of taste sensation, loss of appetite,dizziness, drowsiness, headache,sleep problems (insomnia), dry mouth, sores in the mouth or on the lips,nausea, diarrhea, constipation or mild skin itching or rash. Captopril http://www.rxpharmacy.md/
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