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Methods of action of Amoxicillin antibiotics on Bacterial Infections by Any lainak





Methods of action of Amoxicillin antibiotics on Bacterial Infections by
Article Posted: 10/28/2011
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Articles Written: 159
Word Count: 397
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Methods of action of Amoxicillin antibiotics on Bacterial Infections


 
Health
Amoxicillin is an antibiotic that belongs to a class of antibiotics called penicillins. These antibiotics all have a similar mechanism of action. They do not kill bacteria, but they stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Amoxicillin is effective against many different bacteria including H. influenzae, N. gonorrhoea, E. coli, Pneumococci, Streptococci, and certain strains of Staphylococci. Amoxicillin is stable in the presence of gastric acid and is rapidly absorbed after oral administration. Amoxicillin diffuses readily into most body tissues and fluids, with the exception of brain and spinal fluid, except when meninges are inflamed. The half-life of amoxicillin is 61.3 minutes. Most of the amoxicillin is excreted unchanged in the urine; its excretion can be delayed by concurrent administration of probenecid. In blood serum, amoxicillin is approximately 20% protein-bound. Amoxicillin is indicated in the treatment of infections due to susceptible (ONLY ß-lactamase–negative) strains of the designated microorganisms in the conditions listed below: Infections of the ear, nose, and throat –due to Streptococcus spp. (a- and ß-hemolytic strains only), Streptococcus pneumoniae, Staphylococcus spp., or H. influenzae. Infections of the genitourinary tract – due to E. coli, P. mirabilis, or E. faecalis. Infections of the skin and skin structure – due to Streptococcus spp. (a- and ß-hemolytic strains only), Staphylococcus spp., or E. coli. Infections of the lower respiratory tract due to Streptococcus spp. (a- and ß-hemolytic strains only), S. pneumoniae, Staphylococcus spp., or H. influenzae. Gonorrhea, acute uncomplicated (ano-genital and urethral infections) due to N. gonorrhoeae (males and females). H. pylori eradication to reduce the risk of duodenal ulcer recurrence Dosage and direction To treat different sorts of infections Trimox should be administered 250 mg every eight hours, 500 mg every eight hours, 500 mg each twelve hours or 875 mg every twelve hours. Take with a full glass of water with or without a meal. For children the dosage should be reduced. Possible side effect The most common side effects of Trimox are heartburn, diarrhea, vomiting, dizziness, nausea, insomnia, confusion, abdominal pain, easy bruising or bleeding, rash, itching,and allergic reactions. If adverse effects become bothersome or serious check with your doctor.

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