Lately with the advancement in technology, people have started realising that the ageing phenomenon can also be treated. Hormone Replacement Therapy is the biggest gift of technology for the ageing people. There has been mixed responses on the use of hormone replacement therapy but the majority of them are actually happy and satisfied with the results. Seeing the response, the market for hormone replacement therapy has been growing lately. To facilitate the physicians with the hands on experience and knowledge on this subject, a lot many anti-ageing seminars have started where the experts from around the globe participate and present their research paper on the topic. While diagnosing a patient for hormone replacement therapy, the physicians have to follow some guidelines prepared by the medical council where the experts from 45 countries sat together and prepared it. The guidelines have been broadly classified into two categories. The first one is the prognosis and the second one is the treatment. During prognosis the physician has to make sure to conduct various tests as mentioned in the guidelines scheduled for each visit. During the first visit of the patient the physician must conduct lipid profile, liver function test, mammography, urinalysis, bone biochemistry, blood pressure measurement and monitoring of the levels of follicular stimulating hormone, oestradiol which confirms the presence or absence of menopause and luntensing hormone. For each subsequent visits of the patient till two years, the physician should regularly conduct urinalysis test and blood pressure measurements. Followed by this, every two years the physician should regularly conduct lipid profile, physical examination, liver function test, mammography and determination of the fasting glucose level. If the physician feels the need of bone mineral density at any of the stages, then it can also be conducted on the patient. The hormone replacement therapy guidelines for the treatment mention that, once the physician and the patient have decided to go for hormone replacement therapy then, the first step which the physician should see is that whether any contraindication exist or not in the patient’s body. If the level of contraindication is high, then the physician should drop the idea of hormone replacement therapy. If no contraindication is seen and all the baseline studies are done then the physician needs to focus on the next step. If previous hysterectomy exists then unopposed oestrogen therapy needs to be followed. If intact uterus and amenorrhea exist for less than 2 years then sequential hormone replacement therapy needs to be followed and if intact uterus and amenorrhea exist for more than 2 years then continuous hormone replacement therapy needs to be followed. As a part of guidelines it is mentioned that after every 2 years a check-up should be done.
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