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Chronic obstructive pulmonary disease (COPD) is a regarded to be the most common infection of the lungs that hinders with the normal breathing process. It is characterized with two forms namely chronic bronchitis (a long term cough complication along with mucus) and the other emphysema (causing complete destruction of lungs with time). While, COPD exacerbation is known as worsening of the symptoms associated with this condition. A recent research conducted in this regard has shown that the treatment with amoxicillin or clavulanate potassium aids in alleviating the exacerbations in mild to moderate COPD patients along with significantly extending the time period between the symptom worsening. The researchers performed a randomized, double-blind, controlled clinical trial to prove that the treatment with antibiotic is far more efficient and effective in its action in the COPD patients as compared to placebo. Antibiotics medicine are like amoxil, zantac, cipro these are used to treat bactarial infection in human body and its work same as branded medicine, buy with cheap price these all generic medicine its give the same result as branded drugs. Getting into the clinical details of the study The multicenter, placebo controlled study took into account around 310 COPD confirmed patients in the age group of more than 40 years, who received either of the two antibiotic medications amoxicillin/ clavulanate (with concentration 500 mg/125 mg) and placebo thrice a day for around eight days. The results showed a difference of around 14.2% in the treatment rates in the antibiotic group as compared to the placebo and the median exacerbation time was extended to 233 (in the antibiotic group) from 160 (in the control group). The CRP (C-reactive protein) levels were found to be a brilliant predictor of the treatment results; as patients with below 40 mg/I CRP levels were more likely to be healed without using the antibiotic medications. Hence, the 40 mg/l value of CRP forms the cut off limit that plays a significant role in determining the final outcome. Few of the limitations associated with the study were limited size of the sample, lack of peak flow measurements and no proper objective symptom assessment at the follow-up. The researchers thereby concluded that the study results proved that antibiotic very far more effective than placebo in treating the moderate level exacerbation related to COPD and in particular, those with heightened CRP levels. Hence, this study in general can be claimed as a significant one for COPD patients to relieve their symptoms effectively. Finn is a Medical Student and a freelancer who is specialized in writing. He is associate with many Pharmacies for whom he writes articles based on generic drugs like Cialis Jelly, Penegra Usage, Zenegra USA, Kamagra Fizz and general health related issues.
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