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The Developmental Psychological Stress Can Cause Mental Illness by Code Blue





The Developmental Psychological Stress Can Cause Mental Illness by
Article Posted: 02/07/2013
Article Views: 79
Articles Written: 1725
Word Count: 396
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The Developmental Psychological Stress Can Cause Mental Illness


 
Health
Core Tip: the researchers said in Science magazine that animal experiments show the developmental psychological stress can cause mental illness, and the reason is mainly determined by the dual factors of genetic variation and growth environment. This discovery will help to develop drugs to treat mental illness.

Depression and other mental illness are regarded as have the relationship with the developmental stages of psychological pressure, but people could not have the reason. The researchers of Japan Mei jo University Department of Pharmacy reported in Science magazine that animal experiments show the developmental psychological stress can cause mental illness, and the reason is mainly determined by the dual factors of genetic variation and growth environment. This discovery will help to develop drugs to treat mental illness.

The researchers cultured mice which carry a specific gene variant. This gene variant may be associated with the incidence of mental illness. Since mice born from five weeks (equivalent to human adolescence), the researchers isolated them in the different cages for three weeks in a row, and give the distress to mice. After three weeks, the mice have the symptoms such as allergic reactions sound and demoralized.

If the mice with the specific gene variant were feed collectively, mice do not appear the symptoms of mental illness. Gene normal mice will not develop the disease even isolation rearing. The leader of the research team, Nabeshima who is Meijo University Distinguished Professor said: "This shows that the mental illness have the two factors like the role of both genetic and environmental factors."

The researchers also found that the incidence of mice will be some exceptions, such as the amount of stress hormones in the blood increase. Attention and decision-making neural circuits cannot produce specific enzymes in the brain, and nerve conduction substances like the dopamine’s amount will decline and the efficiency will reduce. However, after the tested mice were injected in the hormone receptors to block the stress, the corresponding symptoms improve. Because of this founding, the researcher could develop the drugs to treat the metal illness. For many patients and families, this founding is good information for them.

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