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What is Lupus erythematosus by Henry yan





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What is Lupus erythematosus by
Article Posted: 04/01/2013
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What is Lupus erythematosus


 
Health
Definition of lupus: Lupus is an autoimmune diseases characterized by chronic inflammation of various tissues of the body. Autoimmune means that the body’s tissues are attacked by its own immune system. The presence of the autoimmune is the appearances of large numbers of circulating auto antibodies against DNA, platelets, erythrocytes, nuclear materials (antinuclear antibodies – ANA). Those auto antibodies can influence the muscles and joints, or some internal main organs, cause pains or even worse damages. The detailed causes of lupus: The immune system within people’s bodies is a complicated system that aims to fight bacteria and other foreign microbes. One of the ways that the immune system fights infections is by producing antibodies. But abnormal antibodies are produced by the lupus patients in their blood that will destroy tissues of their own body rather than foreign infectious agents. Since the antibodies and accompanying cells of inflammation can affect tissues anywhere in the body, lupus has the potential to affect a variety of areas. Some prescription drugs have been reported to produce lupus symptoms but drug induced SLE is rare and usually resolves when the medication is discontinued. Genetic factors increase the tendency of developing autoimmune diseases, such as lupus. The forms of lupus: Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and nervous system, from which we can divide lupus into three main forms. When only the skin is involved, the condition is called subacute cutaneous lupus erythematosus(SCLE). A form of lupus dermatitis that can be isolated to the skin, without internal disease, is called discoid lupus erythematosus. It produces a red, scaly rash which can appear all over the body and leave scars. When internal organs are involved, the condition is named as systemic lupus erythematosus (SLE). Systematic lupus erythematosus is the most common and debilitating form which can cause inflammation of the joints, tendons, connective tissue and major organs such as the kidneys and heart. Otherwise, the most obvious symptom is a butterfly-shaped rash which occurs across the cheeks and nose. The common population who are easy to be affected by the Lupus Women are easier to be affected by lupus comparing to men. The Lupus mainly makes effect on women between the ages of 15 – 45. It is researched that it is more frequent in African Americans and those people of Chinese or Japanese descent. Inherited genes, viruses, ultraviolet light and certain prescription drugs may all play a part. Immune thyroid disease and rheumatoid arthritis are more common among relatives of patients with lupus than the general population. The prevalence of the disease in premenopausal women may be due to the female sex hormones, in particular oestrogen levels. Lupus is more common among relatives of patients with lupus than the general population. Some scientists believe that the immune system in lupus is more easily stimulated by external factors like viruses or ultraviolet light. Sometimes, symptoms of lupus can be precipitated or aggravated by only a brief period of sun exposure.

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