The Platelet Aggregation Kit is used to identify normal and abnormal platelet function, to quantitate platelet response and to determine the patient's response to anti-platelet drug therapy. The reagents are optimized for use with the Helena AggRAM analyzer, but may be used on any turbidometric aggregometer of similar quality. ADP is a lyophilized preparation of adenosine-5-diphosphate. ADP is for use in routine platelet aggregation studies for the evaluation of qualitative platelet function disorders. The concentration of the reconstituted ADP reagent is 20 mM. The collagen reagent is a clear, stabilized liquid reagent prepared from equine tendon, which is one of the world's best collagen preparations. Collagen is used in routine platelet aggregation studies for evaluation of qualitative platelet function disorders. The collagen reagent stock solution is reconstituted to a concentration of 100 µg/mL. Epinephrine is a lyophilized preparation of L-epinephrine bitartrate. Epinephrine is for use in routine platelet aggregation studies for evaluation of qualitative platelet function disorders. After reconstitution, epinephrine concentration is 300 mg. This Ristocetin is for use in platelet aggregation studies for confirmation of von Willebrand Disease (vWD) and Bernard-Soulier Syndrome. Normal platelet-rich plasma exhibits a positive aggregation response to the addition of ristocetin using a final concentration of 12-15 mg/mL. The majority of vWD patients exhibit a negative response to ristocetin as do Bernard-Soulier patients. Helena's platelet reagents provide outstanding stability and performance at affordable pricing. Reagents are optimized for use with AggRAM, but may be used on any turbidometric aggregometer of similar quality. About the Author: Related Articles -
cholesterol electrophoresis, lipoprotein a, Lpa, Lp(a), Lipoprotein(a), platelet aggregation, occult bleeding, bowel cancer screening, test for occult,
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