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Diabetes Will Affect the Alzheimer by Code Blue





Diabetes Will Affect the Alzheimer by
Article Posted: 04/04/2013
Article Views: 95
Articles Written: 1725
Word Count: 434
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Diabetes Will Affect the Alzheimer


 
Health
With the aging of population process accelerated, many diseases have become the killer of the health of the elderly, such as type 2 diabetes and Alzheimer's. According to statistics, the incidence rate of Alzheimer of people who are more than 65 years old is about 5%. The latest research results show that diabetes have the close relationship with the Alzheimer. Elderly people with diabetes have the high risk to suffer from Alzheimer.

Alzheimer has the close relationship with the diabetes.

According to the Diabetes Society of the Chinese Medical Association website released news that an elderly Mexican American population said that type 2 diabetes have the strongly related with the Alzheimer's or cognitive impairment.

The study included 1617 cases: the subjects are people who are 60 to 98 years without dementia or cognitive impairment Mexican American, after 10 years, 41.9% of the subjects with diabetes mellitus, the follow-up period of 9.8% the diagnosis of dementia or cognitive impairment, 22.3% of the subjects died.

Expert said that treated diabetes and untreated diabetes and dementia / cognitive impairment are associated with increased risk of death. After correcting the death of competitive factors, comparing with health people, untreated diabetes still have the relationship with the dementia or cognitive function.

In fact, the relationship research between diabetes and Alzheimer's is not new. Due to the diabetic hyperglycemic state has the large impact to the systemic vascular, several years ago, some experts put forward that vascular abnormalities of the brain and abnormal glucose metabolism may lead to brain function.

At present, experts think that formation mechanism of diabetic patients and Alzheimer's could let the small artery vascular basilemma hyaline degeneration in the brain, which cause endothelial cell damage. At the same time, the brain hemodynamics, vascular reactivity and auto-adjustment function is affected, so the blood flow in the brain will decrease, thereby increasing the incidence of clinically asymptomatic cerebral infarction.

In addition, it may be due to the blood sugar of diabetics with poorly controlled blood glycosylated hemoglobin increased insulin resistance, oxidative stress and inflammatory substances generated, their metabolism of glucose, lipids and amino acids in the brain tissue disorder, which affects the brain within neurons neurotransmitter passing and local micro-environment of change, a long period of ischemia and hypoxia and brain tissue, eventually causing neuronal necrosis and apoptosis and cognitive decline occurs.

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