Amazines Free Article Archive
www.amazines.com - Tuesday, August 05, 2025
Read about the most recent changes and happenings at Amazines.com
Log into your account or register as a new author. Start submitting your articles right now!
Search our database for articles.
Subscribe to receive articles emailed straight to your email account. You may choose multiple categories.
View our newest articles submitted by our authors.
View our most top rated articles rated by our visitors.
* Please note that this is NOT the ARTICLE manager
Add a new EZINE, or manage your EZINE submission.
Add fresh, free web content to your site such as newest articles, web tools, and quotes with a single piece of code!
Home What's New? Submit/Manage Articles Latest Posts Top Rated Article Search
Google
Subscriptions Manage Ezines
CATEGORIES
 Article Archive
 Advertising (133577)
 Advice (161673)
 Affiliate Programs (34799)
 Art and Culture (73858)
 Automotive (145728)
 Blogs (75623)
 Boating (9851)
 Books (17224)
 Buddhism (4130)
 Business (1331078)
 Business News (426461)
 Business Opportunities (366526)
 Camping (10974)
 Career (72796)
 Christianity (15854)
 Collecting (11638)
 Communication (115089)
 Computers (241958)
 Construction (38977)
 Consumer (49954)
 Cooking (17080)
 Copywriting (6734)
 Crafts (18203)
 Cuisine (7549)
 Current Affairs (20323)
 Dating (45910)
 EBooks (19704)
 E-Commerce (48279)
 Education (185537)
 Electronics (83525)
 Email (6438)
 Entertainment (159864)
 Environment (29004)
 Ezine (3040)
 Ezine Publishing (5454)
 Ezine Sites (1551)
 Family & Parenting (111012)
 Fashion & Cosmetics (196613)
 Female Entrepreneurs (11853)
 Feng Shui (134)
 Finance & Investment (310640)
 Fitness (106493)
 Food & Beverages (63058)
 Free Web Resources (7941)
 Gambling (30227)
 Gardening (25207)
 Government (10519)
 Health (630194)
 Hinduism (2206)
 Hobbies (44083)
 Home Business (91754)
 Home Improvement (251315)
 Home Repair (46263)
 Humor (4729)
 Import - Export (5462)
 Insurance (45105)
 Interior Design (29639)
 International Property (3488)
 Internet (191034)
 Internet Marketing (146690)
 Investment (22864)
 Islam (1161)
 Judaism (1352)
 Law (80500)
 Link Popularity (4596)
 Manufacturing (20933)
 Marketing (99329)
 MLM (14140)
 Motivation (18237)
 Music (27000)
 New to the Internet (9498)
 Non-Profit Organizations (4049)
 Online Shopping (129743)
 Organizing (7813)
 Party Ideas (11855)
 Pets (38165)
 Poetry (2229)
 Press Release (12691)
 Public Speaking (5643)
 Publishing (7566)
 Quotes (2407)
 Real Estate (126918)
 Recreation & Leisure (95497)
 Relationships (87678)
 Research (16182)
 Sales (80369)
 Science & Technology (110300)
 Search Engines (23525)
 Self Improvement (153318)
 Seniors (6224)
 Sexuality (36012)
 Small Business (49403)
 Software (83054)
 Spiritual (23537)
 Sports (116156)
 Tax (7664)
 Telecommuting (34070)
 Travel & Tourism (308303)
 UK Property Investment (3123)
 Video Games (13382)
 Web Traffic (11803)
 Website Design (56951)
 Website Promotion (36673)
 World News (1000+)
 Writing (35853)
Author Spotlight
LEMUEL ASIBAL

Lemuel Asibal is a web content writer who also ventures on writing articles and blog posts about any...more
LINDA HOLLAND

I am a passionate article and blog writer based in South Africa. With a love for life and a strong d...more
JOSEPH ZHOU

China Care Medical has been exporting out Chinese medical equipment for many different countries. We...more
HEINZ RAINER

Thirty years Africa, Asia, Europe | Worked in Industry, Trade | preferred Nations : China, Thailand,...more
AREESH ISHTIAQ

Areesh Ishtiaq a Top Rated SEO and Digital Marketing Guru on Upwork, working as a project manager fo...more


Genes and vascular risk modify effects of aging on brain andcognition - Car Code Scanner by grass lawn





Article Author Biography
Genes and vascular risk modify effects of aging on brain andcognition - Car Code Scanner by
Article Posted: 06/15/2013
Article Views: 88
Articles Written: 975
Word Count: 672
Article Votes: 0
AddThis Social Bookmark Button

Genes and vascular risk modify effects of aging on brain andcognition - Car Code Scanner


 
Business,Business News,Business Opportunities
"Everybody ages differently. By looking at genetic variationsand individual differences in markers of vascular health, we beginto understand that preventable factors may affect our chances forsuccessful aging," said Wayne State University psychologydoctoral student Andrew Bender, lead author of a study supported bythe National Institute on Aging of the National Institutes ofHealth and now in press in the journal Neuropsychologia . The report, "Age-related Differences in Memory and ExecutiveFunctions in Healthy APOE ε4 Carriers: The Contribution ofIndividual Differences in Prefrontal Volumes and Systolic BloodPressure," focuses on carriers of the ε4 variant ofthe apolipoprotein (APOE) gene, present in roughly 25 percent ofthe population. Compared to those who possess other forms of theAPOE gene, carriers of the ε4 allele are at significantlygreater risk for Alzheimer's, dementia and cardiovascular disease.

Many studies also have shown that nondemented carriers of the APOEε4 variant have smaller brain volumes and perform less wellon cognitive tests than carriers of other gene variants. Thosefindings, however, are not consistent, and a possible explanationmay come from examining interactions between the risky genes andother factors, such as markers of cardiovascular health. Priorresearch in typical samples of older adults has shown that indeedother vascular risk factors -- such as elevated cholesterol,hypertension or diabetes -- can exacerbate the impact of the APOEε4 variant on brain and cognition, but it is unclear ifsuch synergy of risks is present in healthy adults. Thus, Wayne State researchers evaluated a group of volunteers from19 to 77 years of age who self-reported as exceptionally healthy ona questionnaire that screened for a number of conditions,representing a "best case scenario" of healthy aging.

Theresearch project, led by Naftali Raz, Ph.D., professor ofpsychology and director of the Lifespan Cognitive NeuroscienceResearch Program at WSU's Institute of Gerontology, testeddifferent cognitive abilities known for their sensitivity to agingand the effects of the APOE ε4 variant. Those abilitiesinclude speed of information processing, working memory (holdingand manipulating information in one's mind) and episodic memory(memory for events). Researchers also measured participants' blood pressure, performedgenetic testing to determine which APOE variant participantscarried, and measured the volumes of several critical brain regionsusing a high-resolution structural magnetic resonance imaging brainscan. Bender and Raz showed that for older APOE ε4carriers, even minor increases in systolic blood pressure (thehigher of the two numbers that are reported in blood pressuremeasures) were linked with smaller volumes of the prefrontal cortexand prefrontal white matter, slower speed of informationprocessing, reduced working memory capacity and worse verbalmemory. Notably, they said, that pattern was not evident in thosewho lacked the ε4 gene variant.

The study concludes that the APOE ε4 gene may make itscarriers sensitive to negative effects of relatively subtleelevations in systolic blood pressure, and that the interplaybetween two risk factors, genetic and physiological, is detrimentalto the key brain structures and associated cognitive functions. "Although genes play a significant role in shaping the effectsof age and vascular risk on the brain and cognition, the impact ofsingle genetic variants is relatively small, and there are quite afew of them. Thus, one's aging should not be seen through the lensof one's genetic profile," cautioned the study's authors. Theycontinued, "The negative impact of many genetic variationsneeds help from other risk factors, and while there isn't much onecan do about genes, a lot can be done about vascular risk factorssuch as blood pressure or cholesterol." "Everybody should try to keep those in check, although peoplewith certain genetic variants more so than others." Raz said."Practically speaking, even with the best deck of geneticcards dealt to you, it still makes sense to reduce risk throughwhatever works: exercise, diet or, if those fail, medication." Because the study is part of a longitudinal project, he and Bendersaid the immediate future task now is to determine how theinteraction between risky genes and vascular risk factors affectthe trajectory of age-related changes -- not differences, as inthis cross-sectional study -- in brain and cognition.

I am an expert from carcodescanner.com, while we provides the quality product, such as Car Code Scanner , Heavy Duty Diagnostic Tools, Ecu Chip Tuning,and more.

Related Articles - Car Code Scanner, Heavy Duty Diagnostic Tools,

Email this Article to a Friend!

Receive Articles like this one direct to your email box!
Subscribe for free today!

 Rate This Article  
Completely useless, should be removed from directory.
Minimal useful information.
Decent and informative.
Great article, very informative and helpful.
A 'Must Read'.

 

Do you Agree or Disagree? Have a Comment? POST IT!

 Reader Opinions 
Submit your comments and they will be posted here.
Make this comment or to the Author only:
Name:
Email:
*Your email will NOT be posted. This is for administrative purposes only.
Comments: *Your Comments WILL be posted to the AUTHOR ONLY if you select PRIVATE and to this PUBLIC PAGE if you select PUBLIC, so write accordingly.
 
Please enter the code in the image:



 Author Login 
LOGIN
Register for Author Account

 

Advertiser Login

 

ADVERTISE HERE NOW!
   Limited Time $60 Offer!
   90  Days-1.5 Million Views  

 

Great Paranormal Romance


STEPHEN BYE

Stephen Bye is a fiction writer. His most recent novels are a 5-book “The Developer” series which be...more
ALEX BELSEY

I am the editor of QUAY Magazine, a B2B publication based in the South West of the UK. I am also the...more
PAUL PHILIPS

For more articles, blog messages & videos and a free e-book download go to www.NewParadigm.ws your p...more
TIM FAY

After 60-plus years of living, I am just trying to pass down some of the information that I have lea...more
LAURA JEEVES

At LeadGenerators, we specialise in content-led Online Marketing Strategies for our clients in the t...more
LEVAL AINAH

I am an internet marketer and also an educator. My goal is to help others who are looking to improve...more
STEVERT MCKENZIE

Stevert Mckenzie, Travel Enthusiast. ...more
GENE MYERS

Author of four books and two screenplays; frequent magazine contributor. I have four other books "in...more
ADRIAN JOELE

I have been involved in nutrition and weight management for over 12 years and I like to share my kn...more
MICHAEL BRESCIANI

Rev Bresciani is the author of two Christian books. One book is an important and concisely written b...more

HomeLinksAbout UsContact UsTerms of UsePrivacy PolicyFAQResources
Copyright © 2025, All rights reserved.
Some pages may contain portions of text relating to certain topics obtained from wikipedia.org under the GNU FDL license