|
Liposomes are vesicles filled with liquid and they can be used to deliver medicine to cells, for cancer treatment and other issues. The particles are artificially obtained from cell membranes. Even if the compounds are really small, their wonderful characteristics can make them very useful for people. Experts consider the spheres today among the best ways of transporting nutrients to cells through the mouth. Made from phospholipids, which are contained by membranes, liposomes can have two separate layers. The substance also contains cholesterol. A hematologist from Great Britain named Alec D. Bangham noticed the compounds in 1961 and they were used later in fields such as medicine, biochemistry and biology. The specialist mentioned that one part of a molecule from the substance was solvable in water and another was resistant. The discovery was made accidentally, when Bangham was performing some verification on the electronic microscope of his institute. The test was made by drying phospholipids with a negative stain. Pictures were created and these were the first evidence of the bilayer structure of human cell membranes. If there is a disruption in a membrane, phospholipids can reorganize in the form of spheres, no matter if they are monolayer, or bilayer. Dual versions are the type of compounds that scientists call liposomes and the single ones are called micelles. The substances are taken from the natural content of cell membranes, but this is made artificially. In the natural state of a cell, membranes have the water soluble part to the exterior, for allowing other substances to enter. According to their structure, the spheres can be classified in two types: multi-lamellar and uni-lamellar. Certain properties make the substance unique: structural stability for dilution, the double layer is permeable to some types of molecules, fluidity and the ability to transport soluble and insoluble compounds. The characteristics are not fixed, as they can depend on factors like ionic strength, nearby molecules and temperature. People can use liposomes in the best way if they encapsulate drugs in them. The spheres are are the primary nano pharmaceutical compounds ever used. The term can be split in "Lipos"(fat) and "Somos" (body), from the Greek language. In cases in which phospholipids are placed in water based solutions, the insoluble parts of molecules separate themselves from the fluid, just like vinegar does not mix with oil. With the use of encapsulation, ingesting Vitamin C and taking it directly to the cells has never been easier. There are theories that the compound contains some therapeutic agents, but research did not show any obvious proof yet. According to one of the theories, phospholipids are considered fat by the human liver, which means Vitamin C is released. Scientists also assume that cells steal materials from the compound for repairing their own membranes and this process, again, can lead to leaks. The conclusion could be that liposomes can be great means of transporting different types of materials to human cells, as they were part of membranes before. Despite their microscopic size, the compounds can have multiple characteristics. Scientists say that there are healing properties involves, but there is no proof of this for now. We have all the detailed info about liposome manufacturing on our relevant page. Simply use this link to reach the main website at http://www.encapsula.com.
Related Articles -
Liposomes, liposome formulation, Liposome Manufacturing,
| 
