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The virus, after entering the body, affects blood. Since blood is flowing all over the body, it can affect several body parts at a time. Immune system responds by producing IgM and IgG antibodies directed against the virus. General Symptoms: - Symptoms occur 4 - 7 days after the mosquito bite and typically persist for 3 - 10 days. • Skin rash as a result of tiny hemorrhages inside the skin • Sudden fever and chills • Bradycardia and low blood pressure • Severe muscles and joints ache • Swollen lymph nodes • Eye pain and redness Dengue shock syndrome – It is worst form which can progress into death. Symptoms include:- • Abdominal pain • Sudden drop in blood pressure • Ruptured blood vessels • Hemorrhage • Vomiting • Internal bleeding leading to black vomit and feces. Diagnosis:- It can be difficult to diagnose because of similarity of symptoms with those of west Nile virus infection and chikungunya. • Blood tests to recognize presence of virus • Test RT-PCR (reverse transcriptase-polymerase chain reaction)to measure IgM and IgG levels • Test ELISA (enzyme-linked immunosorbent assay) • Test HI assay (hemagglutination inhibition assay) • Plaque Reduction and Neutralization Test (PRNT) Complications:- • Damage to brain due to bleeding • Liver failure • Myocarditis-Inflammation of the heart muscles • Encephalopathy Treatment:- There are no specific antibiotics for dengue. Hence course of treatment is directed to relieve the symptoms. • Painkillers like aspirin, paracetamol • Nonsteroidal anti-inflammatory drugs like ibuprofen • Hydration • IV drip • Hospitalization • Blood transfusion in case of severe hydration Prevention:- There is no vaccine available to preclude the spread of dengue. • Full body clothing-cover as much as possible • Mosquito repellents • Use Insecticide treated bed nets • Use mosquito traps • Stay away from dengue infected places. • Regular cleansing of water sources • Improvement in basic infrastructure like sanitation, water supply • Solid waste management • Breeding of fish/ predatory copepods With proper cleansing and hygienic practices, we can prevent this deadly endemic. Governments should undertake vector control programs for prevention and eradiction. Harry Kelly is the author of these great articles. He works in the freelancer content writer of a famous pharmacy site online currently he is working with xldrugstore.com. In his work he is committed to help men to know more about the benefits of Zydena, Avanafil, Super Avanafil, Udenafil
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