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New equipment design leads to increased fertility rate for ivfpatients - China Hydrophilic Softener by icdenta icdenta





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New equipment design leads to increased fertility rate for ivfpatients - China Hydrophilic Softener by
Article Posted: 06/06/2013
Article Views: 61
Articles Written: 1096
Word Count: 542
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New equipment design leads to increased fertility rate for ivfpatients - China Hydrophilic Softener


 
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A novel system for processing embryos during IVF treatment has beenshown to significantly improve the chances of pregnancy - by morethan a quarter. Pioneered by a Newcastle team of fertility experts at theUniversity and within the NHS, the innovative design of interlinkedincubators provides a totally enclosed and controlled environmentwithin which every step of the IVF process can be performed. Research published in the journal PLoS ONE reveals that the introduction of the new system into the NewcastleFertility Centre at Life, part of the Newcastle Hospitals NHSFoundation Trust, resulted in a 27% increase in pregnancy ratecompared with conventional equipment used in IVF treatment labs. Traditionally, in IVF procedures embryos are cultured inincubators, which provide a controlled environment. However, it isnecessary to check embryo development under the microscope.

This generally involves removing them from the controlledenvironment of the incubators, which may be harmful. The systemdeveloped by the Newcastle team overcomes this problem by enablingall procedures to be conducted within an enclosed and controlledenvironment. Initially the new system was tested extensively to make sure thatit maintained stable environmental conditions (for air quality andtemperature). Subsequent studies on embryos donated to researchshowed a significant increase in the proportion of embryosdeveloping normally over a period of 6-7 days.

After introduction into the laboratories at Newcastle FertilityCentre at Life, the team were able to compare the treatmentoutcomes over a period of three years. The study, found that 45%achieved a clinical pregnancy compared to 32% and 35% in each ofthe preceding two years. This represents a minimum increase of 27%in the clinical pregnancy rate; a clinical pregnancy means that aheart beat was seen on the scan at 7 weeks gestation. The study, which took account of variability between patients,included women aged 37 or less, undergoing their first cycle of IVFor ICSI, and who had more than ten ovarian follicles (thestructures which contain a mature egg).

This is the first and only system of its kind to be installed inthe UK, however, based on the innovative design from the Newcastleteam, similar systems have already been exported to IVF clinics inthe Netherlands, Canada and Thailand. This positive benefit to IVF patients came from investment intocutting edge research in embryonic stem cell research and was funded by the Medical Research Council and OneNorth East. Newcastle University's Professor Mary Herbert who led the researchteam at Newcastle Fertility Centre at Life, part of the NewcastleHospitals NHS Foundation Trust and based at the Centre for Life,said: "Our aim was to keep eggs and embryos in conditions similarto those they would experience naturally - inside a woman's body.This led our team to design and develop a system in which it ispossible to perform all of the technical procedures whilemaintaining stable conditions throughout the IVF process." Alison Murdoch, Professor of Reproductive Medicine who leads theclinical service at Newcastle Fertility Centre at Life said:"Growing good embryos is the key to IVF success and everyone, eventhose who have a very small prospect of success, deserve to havethe best possible chance. Since installing this new technology over850 babies have now been born." Additional References Citations.

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